Nifedipine Impurity 8 CAS 74936-71-3
| CAS No. | 74936-71-3 |
| Molecular Formula | C16H16N2O6 |
| Molecular Weight | 332.31 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 332.31 g/mol gives Nifedipine Impurity 8 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Nifedipine Impurity 8 (CAS 74936-71-3) is a certified pharmaceutical impurity reference standard with the molecular formula C16H16N2O6 and a molecular weight of 332.31 g/mol.
Nifedipine Impurity 8 (C16H16N2O6) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Nifedipine Impurity 8 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H16N2O6 |
| Molecular Weight | 332.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Nitrogen Atoms | 2 |
Related Nifedipine Standards
- Nifedipine Impurity 10 (CAS 114709-68-1)
- Nifedipine Impurity 25 (CAS 73372-63-1)
- Nifedipine EP Impurity B (CAS 50428-14-3)
- Nifedipine EP Impurity A (CAS 67035-22-7)
- Nifedipine impurity 38 (CAS CATO-C4X-141038)
- Nifedipine Metabolite (CAS 34783-31-8)
- Nifedipine Impurity 9 (CAS 21829-09-4)
- Nifedipine (CAS 21829-25-4)
Recommended Standards
- Idarubicin Impurity 8 (CAS 84499-12-7)
- Zanamivir EP Impurity H (CAS 179531-57-8)
- Lercanidipine Impurity 9 (CAS 74936-72-4)
- Fluorescein Impurity 4 (CAS 2318-08-3)
- Ozefloxacin Impurity 8 (CAS 103877-38-9)
- Atogepant Impurity 81 (CAS CATO-C4X-328581)
- Aspirin Impurity A (CAS 99-96-7)
- (6-Morpholinopyridin-3-yl)methanamine hydrochloride (CAS 1195901-58-6)
- (2-(3-Methyl-1,2,4-oxadiazol-5-yl)phenyl)methanol (CAS 879896-55-6)
- 4-Methoxy-5-(3-phenyl-4,5-dihydroisoxazol-5-yl)benzofuran-6-ol (CAS 61340-54-3)
- Indobufen Impurity 73 (CAS CATO-C4X-179273)
- 3-Isobutoxy-4-methoxybenzoic acid (CAS 860562-57-8)
- 2-Ethoxy-2,3-dihydrobenzo[d]oxazole (CAS 503564-44-1)
- Semaglutide Impurity 187 (CAS CATO-C4X-2226187)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com