Paliperidone Impurity 157 CAS 1809004-63-4
| CAS No. | 1809004-63-4 |
| Molecular Formula | C11H13ClN2O |
| Molecular Weight | 224.69 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Paliperidone Impurity 157 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Paliperidone Impurity 157 (CAS 1809004-63-4) is a certified pharmaceutical impurity reference standard with the molecular formula C11H13ClN2O and a molecular weight of 224.69 g/mol.
The molecular framework of Paliperidone Impurity 157 (C11H13ClN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C11H13ClN2O |
| Molecular Weight | 224.69 g/mol |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Paliperidone Standards
- Paliperidone Impurity 36 (CAS 1160915-55-8)
- Paliperidone Impurity 19 (CAS 1388072-44-3)
- Paliperidone Impurity 76 (CAS CATO-C4X-172476)
- Paliperidone Impurity 57 (CAS CATO-C4X-172457)
- Paliperidone Impurity 8 (CAS CATO-C4X-17248)
- Paliperidone Impurity 159 (CAS CATO-C4X-1724159)
- Paliperidone Impurity 55 (CAS CATO-C4X-172455)
- Paliperidone Impurity N11 (CAS 95742-20-4)
Recommended Standards
- N-Nitroso Lorcaserin (CAS 2518136-84-8)
- Suvorexant Impurity 48 (CAS CATO-C4X-181248)
- Lorcaserin impurity 10 (CAS CATO-C4X-114310)
- Emedastine EP Impurity B (CAS 87233-54-3)
- Terbutaline EP Impurity D (CAS 94109-61-2)
- Ceftriaxone Impurity 12 (CAS CATO-C4X-116312)
- Apremilast Impurity 24 (CAS 2487573-01-1)
- 2-(2-Fluoro-3-methoxy-6-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2096998-37-5)
- 2-[5-amino-3-(4-methoxyphenyl)-1H-pyrazol-1-yl]ethanol (CAS 956568-62-0)
- 1-(Quinolin-4-yl)pyrrolidine-3-carboxylic acid (CAS 1284613-81-5)
- 4-(4-Bromophenyl)morpholin-3-one (CAS 634905-12-7)
- 2-Hydrazino-α-(4-hydroxy-3-methoxybenzyl)propionitrile (CAS 40248-56-4)
- 3-Fluoro-5-(4-phenoxyphenyl)isonicotinonitrile (CAS 1266161-20-9)
- Semaglutide impurity 48 (CAS CATO-C4X-222648)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com