Paliperidone Impurity N11 CAS 95742-20-4
| CAS No. | 95742-20-4 |
| Molecular Formula | C12H13FN2O |
| Molecular Weight | 220.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Paliperidone Impurity N11 (CAS 95742-20-4) is a certified pharmaceutical impurity reference standard with the molecular formula C12H13FN2O and a molecular weight of 220.24 g/mol.
Paliperidone Impurity N11 (C12H13FN2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C12H13FN2O |
| Molecular Weight | 220.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Paliperidone Standards
- Paliperidone Impurity 55 (CAS CATO-C4X-172455)
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- Paliperidone Impurity 159 (CAS CATO-C4X-1724159)
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- Paliperidone Impurity 57 (CAS CATO-C4X-172457)
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Recommended Standards
- Lemborexant impurity 18 (CAS CATO-C4X-304218)
- 2-(2-Oxo-2-(pyridin-4-yl)ethylidene)thiazolidin-4-one (CAS 1000932-15-9)
- 2-[2-oxo-2-(pyridin-3-yl)ethylidene]-1,3-thiazolidin-4-one (CAS 1000932-62-6)
- Risperidone EP Impurity M (CAS 84163-77-9)
- Tofacitinib Impurity 225 (CAS 2026634-40-0)
- Gliquidone Impurity 1 (CAS 76746-95-7)
- Orforglipron Impurity 44 (CAS CATO-C4X-323444)
- 1-{4-[(3,4-dichlorobenzenesulfonyl)methyl]-4-hydroxypiperidin-1-yl}-2,2-dimethylpropan-1-one (CAS 865659-58-1)
- 2,6-Difluoro-4-(methylsulfonyl)aniline (CAS 1147557-74-1)
- 4-Phenylcinnoline (CAS 21874-06-6)
- N-(3-ethoxycyclobutyl)thietan-3-amine (CAS 1864590-25-9)
- pTH (13-34) (human) (CAS 81306-64-1)
- Phenoxymethylpenicillin EP Impurity F (2R,4S) (CAS 196701-54-9)
- Semaglutide Impurity 12 (CAS CATO-C4X-222612)
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