Paliperidone Impurity 76 CAS CATO-C4X-172476
| CAS No. | CATO-C4X-172476 |
| Molecular Formula | C10H11ClN2O2 |
| Molecular Weight | 226.66 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Paliperidone Impurity 76 (CAS CATO-C4X-172476, C10H11ClN2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Paliperidone Impurity 76 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 226.66 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H11ClN2O2 |
| Molecular Weight | 226.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Paliperidone Standards
- Paliperidone Impurity 19 (CAS 1388072-44-3)
- Paliperidone Impurity 157 (CAS 1809004-63-4)
- Paliperidone Impurity 36 (CAS 1160915-55-8)
- Paliperidone Impurity 57 (CAS CATO-C4X-172457)
- Paliperidone Impurity 8 (CAS CATO-C4X-17248)
- Paliperidone Impurity 159 (CAS CATO-C4X-1724159)
- Paliperidone Impurity 55 (CAS CATO-C4X-172455)
- Paliperidone Impurity N11 (CAS 95742-20-4)
Recommended Standards
- Atropine Impurity 19 (CAS 14510-37-3)
- Prilocaine impurity 61 (CAS CATO-C4X-193461)
- Salbutamol Impurity 196 (CAS CATO-C4X-1176196)
- Lornoxicam Impurity 1 (CAS 187746-97-0)
- Mometasone Furoate EP Impurity D (CAS 83881-09-8)
- Benzylpenicillin Impurity 78 (CAS CATO-C4X-189978)
- Ceritinib Impurity 62 (CAS CATO-C4X-104862)
- Flufenican (CAS 78863-62-4)
- 4-[(oxolan-2-yl)methyl]-5-sulfanyl-4H-1,2,4-triazol-3-ol (CAS 793678-88-3)
- Fudosteine Impurity 27 (CAS CATO-C4X-144727)
- Esomeprazole Impurity 120 (CAS 358675-51-1)
- Trimethylsilyl 2-((methoxycarbonothioyl)(methyl)amino)acetate (CAS 34653-82-2)
- 4-[3-(piperidin-3-yl)-1H-pyrazole-4-carbonyl]morpholine dihydrochloride (CAS 2060036-42-0)
- Liraglutide Impurity 19 TFA Salt (CAS CATO-C4X-199219)
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