Candesartan Cilexetil Impurity 45 CAS 1821385-89-0
| CAS No. | 1821385-89-0 |
| Molecular Formula | C33H32N6O6 |
| Molecular Weight | 608.64 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Candesartan Cilexetil Impurity 45 (CAS 1821385-89-0, C33H32N6O6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C33H32N6O6, Candesartan Cilexetil Impurity 45 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 608.64 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C33H32N6O6 |
| Molecular Weight | 608.64 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 21.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Nitrogen Atoms | 6 |
Related Candesartan Standards
- Candesartan Cilexetil (CAS 145040-37-5)
- Candesartan Cilexetil EP Impurity C (CAS 1185255-99-5)
- Candesartan Cilexetil EP Impurity D (CAS 1185256-03-4)
- Candesartan Impurity 6 (CAS CATO-C4X-15726)
- Candesartan N2-Glucuronide (CAS 180603-76-3)
- Candesartan Cilexetil Methoxy Analog (CAS 1026042-12-5)
- Candesartan Cilexetil EP Impurity B (CAS 869631-11-8)
- Candesartan Cilexetil EP Impurity E (CAS 914613-35-7)
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