Axitinib Impurity 86 CAS 1824099-80-0
| CAS No. | 1824099-80-0 |
| Molecular Formula | C8H7NO |
| Molecular Weight | 133.15 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Axitinib Impurity 86 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Axitinib Impurity 86 (CAS 1824099-80-0, C8H7NO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Axitinib Impurity 86 (C8H7NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 133.15 g/mol, it falls into the low-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C8H7NO |
| Molecular Weight | 133.15 g/mol |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Nitrogen Atoms | 1 |
Related Axitinib Standards
- Axitinib Impurity 87 (CAS 1824338-82-0)
- Axitinib Impurity 90 (CAS CATO-C4X-107190)
- Axitinib Impurity 25 (CAS 2571-90-6)
- Axitinib Impurity 66 (CAS 2419145-29-0)
- Axitinib Impurity 37 (CAS CATO-C4X-107137)
- Axitinib Impurity N22 (CAS 7597-18-4)
- Axitinib Impurity 13 (CAS 2527-66-4)
- Axitinib Impurity 17 (CAS 20054-45-9)
Recommended Standards
- Diclofenac EP Impurity E (CAS 59-48-3)
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- Ampicillin Trihydrate EP Impurity M (CAS CATO-C4X-144344)
- (S)-3-Amino-4,4-diphenylbutanoic acid hydrochloride (CAS 332062-01-8)
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- 2-Amino-N-methyl-N-(4-(methylthio)benzyl)acetamide (CAS 1178053-68-3)
- 2-Ethylideneadamantane (CAS 13376-16-4)
- 7-Fluorobenzo[b]thiophene-2-carboxamide (CAS 1956371-69-9)
- (S)-2,5-Dioxopyrrolidin-1-yl 2-((tert-butoxycarbonyl)amino)-3-hydroxypropanoate (CAS 39747-65-4)
- Des-Pro36-Tirzepatide (CAS CATO-CPTD788937)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com