Erlotinib Hydrochloride CAS 183319-69-9
| CAS No. | 183319-69-9 |
| Molecular Formula | C22H23N3O4 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Erlotinib Hydrochloride.
Erlotinib Hydrochloride (CAS 183319-69-9), molecular formula C22H23N3O4HCl and molecular weight 429.90 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C22H23N3O4HCl, Erlotinib Hydrochloride contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 429.90 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Erlotinib Hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H23N3O4 HCl |
| Molecular Weight | 429.90 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2009 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Erlotinib Standards
- Erlotinib Impurity 97 (CAS 1012057-39-4)
- Erlotinib Impurity 93 (CAS 1058132-82-3)
- Erlotinib impurity 136 (CAS 1058651-74-3)
- Erlotinib D4 (CAS 1130852-41-3)
- Erlotinib Impurity 123 (CAS 1145671-36-8)
- Erlotinib Hydrochloride Impurity 3 (CAS 1145671-52-8)
- Erlotinib Impurity 51 (CAS 115665-66-2)
- Erlotinib-d6 HCl (CAS 1189953-78-3)
Recommended Standards
- Lead stannate (CAS 12036-31-6)
- 6-(2-Fluorophenoxy)pyridine-3-carboxylic acid (CAS 862088-69-5)
- 2-(2-((Tert-butyldimethylsilyl)oxy)phenyl)acetonitrile (CAS 2338684-84-5)
- N,N-Dimethylphenazin-2-amine (CAS 6494-69-5)
- 5-Bromo-2-chloro-N-(4-methoxybenzyl)pyrimidin-4-amine (CAS 1172925-32-4)
- 5-(Piperidin-3-yl)-7-(trifluoromethyl)imidazo[1,2-a]pyrimidine dihydrochloride (CAS 1185299-45-9)
- 2-(4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)phenoxy)-1-(p-tolyl)ethan-1-one (CAS 339020-07-4)
- Dexamethasone impurity 80 (CAS CATO-C4X-116580)
- 4-Chloro-2-(pyridin-2-yl)-6-(pyridin-3-yl)pyrimidine (CAS 1001915-28-1)
- Cholecystokinin Octapeptide free acid (desulfated) (H-2075.0001) (CAS 103974-46-5)
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