Dexamethasone impurity 80 CAS CATO-C4X-116580
| CAS No. | CATO-C4X-116580 |
| Molecular Formula | C28H39FO9 |
| Molecular Weight | 538.60 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Dexamethasone impurity 80 (C28H39FO9) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Dexamethasone impurity 80 (CAS CATO-C4X-116580) is a certified pharmaceutical impurity reference standard with the molecular formula C28H39FO9 and a molecular weight of 538.60 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Dexamethasone impurity 80 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C28H39FO9 |
| Molecular Weight | 538.60 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Dexamethasone Standards
- Dexamethasone impurity 81 (CAS CATO-C4X-116581)
- Dexamethasone Decanoate (CAS CATO-C4X-116571)
- Dexamethasone Impurity 01 (CAS 83880-70-0)
- Dexamethasone impurity 78 (CAS 1879-72-7)
- Dexamethasone 21-O-β-D-galactopyranoside (CAS 92901-23-0)
- Dexamethasone Impurity 88 (CAS CATO-C4X-116588)
- Dexamethasone undecylate (CAS CATO-C4X-116576)
- Dexamethasone Impurity 118 (CAS CATO-C4X-1165118)
Recommended Standards
- rel-(2R,2'R,3R,3'R)-3,3'-di-tert-Butyl-4,4'-diphenyl-2,2',3,3'-tetrahydro-2,2'-bibenzo[d][1,3]oxaphosphole (CAS 2301856-53-9)
- Phospholane, 1,1′-(1,2-ethanediyl)bis[2,5-diphenyl-, 1,1′-dioxide, (2R,2′R,5R,5′R)- (CAS 528565-82-4)
- Pemetrexed Impurity 71 (CAS CATO-C4X-172671)
- (2R,2'R,3R,3'R)-Ph-BIBOP (CAS 2719857-97-1)
- Salbutamol Impurity 192 (CAS CATO-C4X-1176192)
- Methylprednisolone impurity 85 (CAS CATO-C4X-191985)
- Upadacitinib Impurity 30 (CAS CATO-C4X-240530)
- N-ethyl-N-methyl-3,4,5,6-tetrahydro-[2,3'-bipyridin]-2'-amine (CAS 1352518-64-9)
- DBCO-PEG6-amine (CAS 2353409-98-8)
- n-(4-Iodophenyl)isoxazole-3-carboxamide (CAS 1249743-38-1)
- Ethyl 5,7-dioxo-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-d]pyrimidine-3-carboxylate (CAS 1207175-72-1)
- Cefmetazole Impurity 26 (CAS CATO-C4X-150726)
- Hydrocortisone Impurity 62 (CAS CATO-C4X-140162)
- Heptapeptide-6 (CAS CATO-CPTD788823)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com