Erlotinib Impurity 10 CAS 183320-51-6
| CAS No. | 183320-51-6 |
| Molecular Formula | C21H21N3O4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Erlotinib Impurity 10 (CAS 183320-51-6), a pharmacopoeial impurity reference standard (molecular formula C21H21N3O4HCl, MW 415.87 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C21H21N3O4HCl, Erlotinib Impurity 10 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 415.87 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C21H21N3O4 HCl |
| Molecular Weight | 415.87 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2009 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Erlotinib Standards
- Erlotinib Impurity 97 (CAS 1012057-39-4)
- Erlotinib Impurity 93 (CAS 1058132-82-3)
- Erlotinib impurity 136 (CAS 1058651-74-3)
- Erlotinib D4 (CAS 1130852-41-3)
- Erlotinib Impurity 123 (CAS 1145671-36-8)
- Erlotinib Hydrochloride Impurity 3 (CAS 1145671-52-8)
- Erlotinib Impurity 51 (CAS 115665-66-2)
- Erlotinib-d6 HCl (CAS 1189953-78-3)
Recommended Standards
- Cefcapene Impurity 104 (CAS CATO-C4X-1824104)
- Esomeprazole Impurity 105 (CAS 86604-78-6)
- Faropenem Impurity 71 (CAS CATO-C4X-128971)
- 5-Cyclopropoxy-2-isopropoxy-4-nitropyridine (CAS 1243365-50-5)
- 1-(4-Bromo-3-chlorophenyl)-2-chloroethanone (CAS 1261859-54-4)
- 1-(2-Hydroxy-6-(trifluoromethyl)phenyl)ethanone (CAS 1024605-96-6)
- 3,4-dihydro-2H-1,5-benzodioxepine-7-carbaldehyde (CAS 67869-90-3)
- Valaciclovir Impurity 56 (CAS CATO-C4X-124856)
- 2-Ethyl-DL-proline Methyl Ester (CAS 1065848-50-1)
- Fragment-[9-31]-Semaglutide (CAS CATO-C4X-2226181)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com