Josamycin EP Impurity K CAS 18361-48-3
| CAS No. | 18361-48-3 |
| Molecular Formula | C40H65NO15 |
| Molecular Weight | 799.94 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Josamycin EP Impurity K under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Josamycin EP Impurity K (CAS 18361-48-3) is a certified pharmaceutical impurity reference standard with the molecular formula C40H65NO15 and a molecular weight of 799.94 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Josamycin EP Impurity K is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 799.94 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C40H65NO15 |
| Molecular Weight | 799.94 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Nitrogen Atoms | 1 |
Related Josamycin Standards
- Josamycin EP Impurity H (KitasaMycin A1) (CAS 16846-34-7)
- Josamycin Impurity M (CAS 18361-50-7)
- Josamycin EP Impurity A (CAS 18361-46-1)
- Josamycin EP Impurity D (Isoleucomycin A3) (CAS 22340-94-9)
- Josamycin Impurity 8 (CAS CATO-C4X-30158)
- Josamycin EP Impurity B (18-Dihydroleucomycin A3) (CAS 40361-41-9)
- Josamycin EP Impurity I (CAS 18361-47-2)
- Josamycin Impurity 7 (CAS CATO-C4X-30157)
Recommended Standards
- Polyethylene glycol monomyristate (CAS 9004-89-1)
- Sovaprevir (CAS 1001667-23-7)
- 4-Thio-DU CEP (CAS 144303-74-2)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com