Fosaprepitant Impurity 52 CAS CATO-C4X-116852
| CAS No. | CATO-C4X-116852 |
| Molecular Formula | C26H24F7N7O4 |
| Molecular Weight | 631.50 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Fosaprepitant Impurity 52 (C26H24F7N7O4) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 631.50 g/mol, it falls into the high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Fosaprepitant Impurity 52 (CAS CATO-C4X-116852), a pharmacopoeial impurity reference standard (molecular formula C26H24F7N7O4, MW 631.50 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Fosaprepitant Impurity 52 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H24F7N7O4 |
| Molecular Weight | 631.50 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 7 |
Related Fosaprepitant Standards
- Fosaprepitant impurity 10 (CAS CATO-C4X-116810)
- Fosaprepitant Impurity 35 (CAS CATO-C4X-116835)
- Fosaprepitant Impurity 47 (CAS CATO-C4X-116847)
- Fosaprepitant Impurity 2 (CAS CATO-C4X-11682)
- Fosaprepitant Impurity 5 (CAS CATO-C4X-11685)
- Fosaprepitant Impurity 46 (CAS CATO-C4X-116846)
- Fosaprepitant Impurity 34 (CAS CATO-C4X-116834)
- Fosaprepitant Impurity 43 (CAS CATO-C4X-116843)
Recommended Standards
- Lifitegrast Impurity 90 (CAS CATO-C4X-240990)
- (SP-4-1)-[29H,31H-Phthalocyanine-1,8,15,22-tetraminato(2-)-κN29,κN30,κN31,κN32]cobalt (CAS 77135-78-5)
- Lifitegrast Impurity 82 (CAS CATO-C4X-240982)
- Cobaltate(1-), [29H,31H-phthalocyanine-2,9,16,23-tetraminato(2-)-κN29,κN30,κN31,κN32]-, (SP-4-1)- (CAS 203860-42-8)
- Linezolid Impurity 96 (CAS 152139-76-9)
- Pitavastatin Impurity 60 (CAS CATO-C4X-103760)
- Mirogabalin Impurity N75 (CAS CATO-CP155175)
- O-(2-(3-(trifluoromethyl)phenoxy)ethyl)hydroxylamine hydrochloride (CAS 113211-36-2)
- Hexakis(6-Iodo-6-Deoxy)-α-Cyclodextrin (CAS 131105-41-4)
- Pyronaridine Impurity 21 (CAS CATO-C4X-297821)
- 1-[(5Z)-5-[(Dimethylamino)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]pyrrolidine-2,5-dione (CAS 477845-33-3)
- Mitoxantrone Impurity 20 (CAS CATO-C4X-103420)
- 4-(4-(Trifluoromethoxy)phenyl)-2-(4-(trifluoromethyl)benzyl)-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 343373-52-4)
- Semaglutide Impurity 125 xTFA Salt (CAS CATO-C4X-2226125)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com