Montelukast Impurity 29 CAS 184764-13-4

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.184764-13-4
Molecular FormulaC28H24ClNO2
Molecular Weight441.95 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Montelukast Impurity 29 CAS 184764-13-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 441.95 g/mol gives Montelukast Impurity 29 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Montelukast Impurity 29 (CAS 184764-13-4) is a certified pharmaceutical impurity reference standard with the molecular formula C28H24ClNO2 and a molecular weight of 441.95 g/mol.

Montelukast Impurity 29 (C28H24ClNO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Montelukast Impurity 29 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC28H24ClNO2
Molecular Weight441.95 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity>95%
StorageStore at room temperature, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)17.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2009
Halogen ContentCl-containing
Nitrogen Atoms1

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