Montelukast Impurity 32 CAS 1187586-63-5
| CAS No. | 1187586-63-5 |
| Molecular Formula | C29H26ClNO |
| Molecular Weight | 439.98 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Montelukast Impurity 32 (CAS 1187586-63-5) is a certified pharmaceutical impurity reference standard with the molecular formula C29H26ClNO and a molecular weight of 439.98 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Montelukast Impurity 32 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 439.98 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Montelukast Impurity 32 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C29H26ClNO |
| Molecular Weight | 439.98 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Montelukast Standards
- Montelukast Dehydro Impurity (CAS 168214-68-4)
- Montelukast Impurity 27 (CAS 168214-67-3)
- Montelukast Impurity 37 (CAS CATO-C4X-103137)
- Montelukast Impurity 29 (CAS 184764-13-4)
- Montelukast Impurity N19 (CAS 150026-73-6)
- Montelukast Impurity 11 (CAS 120578-04-3)
- Montelukast Impurity 56 (CAS 1100617-38-6)
- Montelukast 3-Oxo Benzoate (CAS 149968-11-6)
Recommended Standards
- N-(1-(4-Chlorophenyl)ethyl)-2-((4-(4-fluorophenyl)-5-thioxo-4,5-dihydro-1,3,4-thiadiazol-2-yl)thio)acetamide (CAS 869866-06-8)
- Loratadine Impurity 41 (CAS CATO-C4X-142641)
- 2-Imino-6,8-diiodo-2H-chromene-3-carboxamide (CAS 1823984-45-7)
- 4-Iodo-2-heptafluoropropoxy-1,1,1,2-tetrafluorobutane (CAS 243128-38-3)
- Edaravone Impurity 16 (CAS CATO-C4X-106216)
- Acetaminophen Impurity 32 (CAS 874-60-2)
- Esomeprazole Impurity 83 (CAS 142885-95-8)
- 4-Acetyl-N-(furan-2-ylmethyl)benzenesulfonamide (CAS 736948-74-6)
- 3-Methyl-2-(oxetan-3-yloxy)benzonitrile (CAS 1696643-09-0)
- 5-(tert-Butyl)-4-cyclopropoxypicolinaldehyde (CAS 1243456-79-2)
- 1-(3-Methoxybenzyl)-1H-imidazole-5-carboxylic acid (CAS 1439900-55-6)
- 4-Bromo-2-methylpyrrolo[1,2-a]pyrimidine-8-carboxylic acid (CAS 1919049-59-4)
- 3-(1h-Pyrrol-1-yl)thiophene-2-carboxylic acid (CAS 74772-17-1)
- Biotinyl-Neuropeptide Y (human, rat) trifluoroacetate salt (CAS 213779-13-6)
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