Bromhexine Impurity 50 CAS 18683-92-6
| CAS No. | 18683-92-6 |
| Molecular Formula | C14H18Br2N2 |
| Molecular Weight | 374.11 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Bromhexine Impurity 50 (CAS 18683-92-6), a pharmacopoeial impurity reference standard (molecular formula C14H18Br2N2, MW 374.11 g/mol) used for the identification and quantification of trace impurities in APIs.
Bromhexine Impurity 50 (C14H18Br2N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Bromhexine Impurity 50 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H18Br2N2 |
| Molecular Weight | 374.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Bromhexine Standards
- Bromhexine Impurity N3 (CAS 114390-41-9)
- Bromhexine (CAS 3572-43-8)
- Bromhexine Impurity 17 (CAS 114390-40-8)
- Bromhexine Impurity N1 (CAS 14860-48-1)
- Bromhexine Impurity 10 (CAS 2512203-87-9)
- Bromhexine Impurity 11 (CAS 21237-84-3)
- Bromhexine Impurity 20 (CAS CATO-C4X-106020)
- Bromhexine Impurity 46 (CAS 3472-84-2)
Recommended Standards
- 2-Deoxy-2-Fluoro-5-Iodo-uridine (CAS 69123-98-4)
- Ethyl 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoroheptanoate (CAS 42287-85-4)
- Gold(III) acetate (CAS 15804-32-7)
- cis-Dichloro(2-aminomethylpyridine)platinum(II) (CAS 64174-32-9)
- Lamivudine EP Impurity I (CAS 145918-75-8)
- Avanafil Impurity 127 HCl (CAS 38057-59-9)
- Propofol Impurity 30 (CAS 2215-89-6)
- (2R)-oxane-2-carboxylic acid (CAS 105499-34-1)
- 1-Methyl-4-(2-(p-tolyl)hydrazono)-3,4-dihydro-1H-thieno[3,2-c][1,2]thiazine 2,2-dioxide (CAS 477845-65-1)
- 2-(4-(N-Butyl-N-ethylsulfamoyl)benzamido)-6-ethyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide (CAS 449767-74-2)
- Poly(oxy-1,2-ethanediyl), .alpha.-(4-sulfobutyl)-.omega.-(4-sulfobutoxy)-, sodium salt (CAS 72361-57-0)
- 1-Isopropyl-1H-pyrrolo[2,3-b]pyridine-2,3-dione (CAS 960155-14-0)
- 1-(4-(Sec-butyl)phenyl)-5-(4-chlorophenyl)-3-methyl-1H-pyrazole-4-carboxylic acid (CAS 956786-71-3)
- Des-Ala28-Tirzepatide (CAS CATO-CPTD788945)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com