Lamivudine EP Impurity I CAS 145918-75-8
| CAS No. | 145918-75-8 |
| Molecular Formula | C8H11N3O4 |
| Molecular Weight | 213.19 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Lamivudine EP Impurity I is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 213.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Lamivudine EP Impurity I (CAS 145918-75-8) is a certified pharmaceutical impurity reference standard with the molecular formula C8H11N3O4 and a molecular weight of 213.19 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Lamivudine EP Impurity I under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H11N3O4 |
| Molecular Weight | 213.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 3 |
Related Lamivudine Standards
- Lamivudine Impurity B (CAS 141434-39-1)
- Lamivudine (CAS 134678-17-4)
- Lamivudine Impurity B((2R,5R)-Isomer) (CAS 139757-68-9)
- Lamivudine Impurity 24 (CAS CATO-C4X-119424)
- Lamivudine EP Impurity B ((2S,5S)-Isomer) (CAS 136846-20-3)
- Lamivudine EP Impurity D (Ent-Lamivudine) (CAS 134680-32-3)
- Lamivudine Impurity J (CAS 131086-26-5)
- Lamivudine EP Impurity J (CAS 145986-07-8)
Recommended Standards
- Sildenafil Impurity 36 (CAS 139756-00-6)
- Omeprazole Impurity 6 (CAS CATO-C4X-12556)
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- Droxidopa Impurity 3 (CAS CATO-C4X-16253)
- Pantoprazole Impurity 26 (CAS 4780-14-7)
- Lansoprazole EP Impurity E (CAS 583-39-1)
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- Tert-butyl 4-((3-(trifluoromethyl)phenyl)amino)piperidine-1-carboxylate (CAS 477864-09-8)
- JNJ 303 (CAS 878489-28-2)
- 1-(2,3-Dimethylcyclohexyl)-1H-benzimidazole-5-carboxylic acid (CAS 953806-84-3)
- Agomelatine Impurity 17 (CAS 92041-01-5)
- 1020718-81-3 2-[2-(2-Amino-6-chloro-9H-purin-9-yl)ethyl-1,1,2,2-d4]-1,3-propanediol 1,3-Diacetate 9-(4-Acetoxy-3-acetoxymethylbutyl)-2-amino-6-chloropurine-d4 (CAS 1020718-81-3)
- 29849-82-9 (R)-2,3-Dihydroxypropyl (dihydrogen phosphate), compound with cyclohexylamine (1:2) 1,2,3-Propanetriol, 1-(dihydrogen phosphate), (2R)-, compd. with cyclohexanamine (1:2) EINECS 249-889-9 L-alpha-Glycerolphosphate, dicyclohexylammonium salt (CAS 29849-82-9)
- Semaglutide Impurity 176 (CAS CATO-C4X-2226176)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com