Tenofovir Alafenamide Impurity 2 CAS 1883563-86-7
| CAS No. | 1883563-86-7 |
| Molecular Formula | C21H36N7O6P |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Tenofovir Alafenamide Impurity 2.
As a process- or degradation-related impurity, Tenofovir Alafenamide Impurity 2 (CAS 1883563-86-7, C21H36N7O6PC4H4O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C21H36N7O6PC4H4O4, Tenofovir Alafenamide Impurity 2 contains a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 629.61 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Tenofovir Alafenamide Impurity 2 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H36N7O6P C4H4O4 |
| Molecular Weight | 629.61 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Nitrogen Atoms | 7 |
Related Tenofovir Standards
- Tenofovir alafenamide Impurity 79 (CAS 102-10-3)
- rac Tenofovir-d6 (CAS 1020719-94-1)
- Tenofovir disoproxil Impurity 142 (CAS 102537-97-3)
- Tenofovir Disoproxil Dimer (CAS 1093279-76-5)
- Tenofovir disoproxil Impurity 6 (CAS 1093279-77-6)
- Tenofovir disoproxil Impurity 28 (CAS 1115-59-9)
- Tenofovir Impurity 59 (CAS 116384-56-6)
- Tenofovir alafenamide impurity 85 (CAS 121149-98-2)
Recommended Standards
- Blonanserin Impurity 37 (CAS 132810-93-6)
- Vortioxetine Impurity 39 (CAS CATO-C4X-105639)
- Metaraminol Impurity 67 (CAS CATO-C4X-225267)
- 3-Methylazetidine (CAS 35196-99-7)
- Sofosbuvir Impurity 123 (CAS 119804-96-5)
- (4-Fluorophenyl)(2-(phenoxymethyl)-6,7-dihydrooxazolo[5,4-c]pyridin-5(4H)-yl)methanone (CAS 1363281-27-9)
- Decahydro-2,7-naphthyridine (CAS 885270-20-2)
- 5-Fluoro-1,3-dimethylpyrimidine-2,4(1H,3H)-dione (CAS 3013-92-1)
- 3-Chloro-3,3-difluoroprop-1-ene (CAS 421-03-4)
- Palmitoyl Tetrapeptide-7 (CAS 221227-05-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com