Rivastigmine Impurity 25 CAS 18840-47-6
| CAS No. | 18840-47-6 |
| Molecular Formula | C9H13NO |
| Molecular Weight | 151.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Rivastigmine Impurity 25 (CAS 18840-47-6) is a certified pharmaceutical impurity reference standard with the molecular formula C9H13NO and a molecular weight of 151.21 g/mol.
Based on its molecular formula C9H13NO, Rivastigmine Impurity 25 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 151.21 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H13NO |
| Molecular Weight | 151.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Nitrogen Atoms | 1 |
Related Rivastigmine Standards
- Rivastigmine Impurity N2 (CAS 894079-42-6)
- Rivastigmine RC 1 (CAS 923035-06-7)
- Rivastigmine EP Impurity G (CAS 23308-82-9)
- Rivastigmine EP Impurity H (CAS 586-37-8)
- Rivastigmine EP Impurity A (CAS 139306-10-8)
- Rivastigmine Impurity 10 (CAS 105601-04-5)
- Rivastigmine Impurity 45 (CAS 26050-44-2)
- Rivastigmine RC 6 (CAS 851086-95-8)
Recommended Standards
- Pioglitazone impurity 60 (CAS 1000564-06-6)
- Phenylephrine Impurity 41 (CAS 51674-33-0)
- Pioglitazone impurity 59 (CAS 102438-88-0)
- Phenylephrine Impurity 79 (CAS CATO-C4X-146779)
- Cyanocobalamin Impurity 29 (CAS 23388-02-5 (unfixed chirality))
- Aprepitant Impurity 81 (CAS CATO-C4X-114181)
- Anastrozole EP Impurity C (CAS 120511-84-4)
- 7-Bromo-4-(pyrimidin-2-ylmethyl)-3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-one (CAS 1448754-42-4)
- 4-Bromo-1-fluoro-2-(4-methylbenzyl)benzene (CAS 1776111-97-7)
- N-Methyl-3-phenoxyaniline (CAS 13024-17-4)
- Ethyl 4-fluoro-3-formylbenzoate (CAS 1806331-01-0)
- 1-(3-Fluoro-4-methoxyphenyl)-1-propanone (CAS 586-22-1)
- thieno[3,2-b]thiophene-2-boronic acid (CAS 160032-40-6)
- Peptide Impurity 64 (CAS CATO-CPTD788964)
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