Rivastigmine Impurity 45 CAS 26050-44-2
| CAS No. | 26050-44-2 |
| Molecular Formula | C10H15NO |
| Molecular Weight | 165.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Rivastigmine Impurity 45 (CAS 26050-44-2, C10H15NO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Rivastigmine Impurity 45 (C10H15NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Rivastigmine Impurity 45 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H15NO |
| Molecular Weight | 165.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Nitrogen Atoms | 1 |
Related Rivastigmine Standards
- Rivastigmine EP Impurity A (CAS 139306-10-8)
- Rivastigmine Impurity 10 (CAS 105601-04-5)
- Rivastigmine RC 6 (CAS 851086-95-8)
- Rivastigmine Impurity N3 (CAS 90271-37-7)
- Rivastigmine Impurity N4 (CAS 58114-05-9)
- Rivastigmine Impurity N13 (CAS 2454-35-5)
- Rivastigmine EP Impurity G (CAS 23308-82-9)
- Rivastigmine Impurity 25 (CAS 18840-47-6)
Recommended Standards
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- Docetaxel Impurity 85 (CAS 1095547-79-7)
- Upadacitinib Impurity 74 (CAS 2650489-63-5)
- Tafluprost Impurity 22 (CAS CATO-C4X-216322)
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- 5-(3-(tert-Butyl)phenyl)-3,4-dimethylisoxazole (CAS 61314-45-2)
- Insulin Degludec Impurity 5 (CAS CATO-C4X-21575)
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