Doxorubicin Impurity N2 HCl CAS 18977-93-0
| CAS No. | 18977-93-0 |
| Molecular Formula | C6H13NO3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, Doxorubicin Impurity N2 HCl is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 183.63 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Doxorubicin Impurity N2 HCl (CAS 18977-93-0), a pharmacopoeial impurity reference standard (molecular formula C6H13NO3HCl, MW 183.63 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Doxorubicin Impurity N2 HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H13NO3 HCl |
| Molecular Weight | 183.63 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Doxorubicin Standards
- Doxorubicin Impurity 7 (CAS 105612-58-6)
- Doxorubicin Impurity N19 (CAS 106401-68-7)
- Doxorubicin Impurity 5 (CAS 1159977-23-7)
- Doxorubicin EP Impurity B (CAS 148218-14-8)
- Doxorubicin-hydrazone-caproyl-maleimide (CAS 151038-96-9)
- Doxorubicin Dimer Impurity 23 (CAS 201278-93-5)
- Doxorubicin Impurity 8 (CAS 20982-41-6)
- Doxorubicin Impurity 39 (Mixture of Diastereomers) (CAS 210837-87-9)
Recommended Standards
- Isavuconazole Impurity 124 (CAS CATO-C4X-1236124)
- Belumosudil Impurity 17 (CAS 97454-48-3)
- Mianserin Impurity 48 (CAS CATO-C4X-136948)
- (5-amino-2,4-dimethylphenyl)methanol (CAS 1334148-06-9)
- Ethyl [4-(acetylamino)phenoxy]acetate (CAS 67202-81-7)
- 6-Bromo-2-hydroxy-5-oxo-5,6,7,8-tetrahydroquinoline-3-carbonitrile (CAS 107955-83-9)
- (2-Methyl-1-piperidinyl)(2-pyrrolidinyl)methanonehydrochloride (CAS 1246172-82-6)
- 3-Phenyl-4-(2,4,6-trimethylbenzyl)isoxazol-5(2H)-one (CAS 89114-13-6)
- Methyl 2-(7-Fluoro-3-indolyl)-2-oxoacetate (CAS 425638-75-1)
- D-Thr5-Tirzepatide (CAS CATO-CPTD788926)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com