Ezetimibe Impurity 129 CAS CATO-C4X-1098129
| CAS No. | CATO-C4X-1098129 |
| Molecular Formula | C24H22F2N2O4 |
| Molecular Weight | 440.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Ezetimibe Impurity 129 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Ezetimibe Impurity 129 (CAS CATO-C4X-1098129) is a certified pharmaceutical impurity reference standard with the molecular formula C24H22F2N2O4 and a molecular weight of 440.44 g/mol.
The molecular framework of Ezetimibe Impurity 129 (C24H22F2N2O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C24H22F2N2O4 |
| Molecular Weight | 440.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Ezetimibe Standards
- Ezetimibe Impurity 109 (CAS CATO-C4X-1098109)
- Ezetimibe Impurity 106 (CAS CATO-C4X-1098106)
- Ezetimibe Impurity 117 (CAS 1013025-04-1)
- Ezetimibe Impurity 18 (CAS 204589-80-0)
- Ezetimibe Impurity 49 (CAS 1044664-24-5)
- Ezetimibe Impurity 1 Sodium salt (CAS 1400989-75-4)
- Ezetimibe Impurity S (CAS 190448-46-5)
- EzetimiBe Impurity 19 (CAS 1391053-63-6)
Recommended Standards
- Diethyl 2,6-dimethyl-4-(5-(2-nitrophenyl)furan-2-yl)-1,4-dihydropyridine-3,5-dicarboxylate (CAS 104024-40-0)
- Suberoylanilide hydroxamic acid β-d-glucuronide (CAS 863456-50-2)
- Candesartan Ethyl Ester Desethyl Analog (CAS 1225044-20-1)
- Pharacine (CAS 63440-93-7)
- Apixaban Impurity 138 (CAS CATO-C4X-1088138)
- Atorvastatin Impurity 95 (CAS 442851-50-5)
- Tadalafil Impurity 134 (CAS 171596-43-3)
- Methyl (S)-2-benzamido-3-(4-hydroxy-3-methoxyphenyl)propanoate (CAS 51593-52-3)
- Phosphoramidic acid, N-(aminoiminomethyl)- (CAS 3019-36-1)
- (1S,2S)-2-(Benzyloxy)cyclohexanol (CAS 85761-39-3)
- 3-(Furan-3-yl)-N-((2-methoxyadamantan-2-yl)methyl)acrylamide (CAS 1798401-52-1)
- 7-Chloro-8-((triisopropylsilyl)ethynyl)naphthalene-1,3-diol (CAS 2771460-17-2)
- 5-(Methylsulfonyl)-4-(m-tolyl)-1,2,3-thiadiazole (CAS 1708380-29-3)
- Semaglutide impurity 210 (CAS CATO-C4X-2226210)
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