Metoprolol EP Impurity C（HCl） CAS 1956321-87-1
| CAS No. | 1956321-87-1 |
| Molecular Formula | C13H19NO3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Metoprolol EP Impurity C（HCl） (CAS 1956321-87-1, C13H19NO3HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Metoprolol EP Impurity C（HCl） is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 273.76 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Metoprolol EP Impurity C（HCl） under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H19NO3 HCl |
| Molecular Weight | 273.76 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Metoprolol Standards
- Metoprolol EP Impurity A (CAS 109632-08-8)
- Metoprolol Impurity 23 (CAS 109632-11-3)
- Metoprolol Impurity 9 (CAS 1155083-53-6)
- Metoprolol Acid-d5 Ethyl Ester (CAS 1189704-28-6)
- Metoprolol Fumarate (CAS 119637-66-0)
- Metoprolol Acid-d5 (CAS 1215404-47-9)
- Metoprolol-D7 Hydrochloride (CAS 1219798-61-4)
- Metoprolol Impurity 22 (CAS 123195-72-2)
Recommended Standards
- Ramelteon Impurity 8 (CAS CATO-C4X-26228)
- Famciclovir impurity 3 (CAS 172529-94-1)
- Ticagrelor Impurity 43 (CAS 145783-13-7)
- 7-Chloro-3-(trifluoromethyl)quinoline-8-carboxylic acid (CAS 114012-29-2)
- 3-Carboethoxyphenyl cyclobutyl ketone (CAS 898790-54-0)
- Methyl 4-cyclopropyl-2,4-dioxobutanoate (CAS 167408-67-5)
- A 77636 Hydrochloride (CAS 145307-34-2)
- 5-Bromo-2-butoxypyrimidine (CAS 1215206-57-7)
- Methyl 1-phenylpiperidine-3-carboxylate (CAS 1822843-87-7)
- (Gly1,Ser3·22,Gln?·3?,Thr?,Arg1?,Tyr21,Ala23·31,Aib32)-Pancreatic Polypeptide (human) (CAS 313988-89-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com