Metoprolol Impurity 22 CAS 123195-72-2
| CAS No. | 123195-72-2 |
| Molecular Formula | C12H18O2 |
| Molecular Weight | 194.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Metoprolol Impurity 22.
As a process- or degradation-related impurity, Metoprolol Impurity 22 (CAS 123195-72-2, C12H18O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C12H18O2, Metoprolol Impurity 22 contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 194.27 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Metoprolol Impurity 22 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H18O2 |
| Molecular Weight | 194.27 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
Related Metoprolol Standards
- Metoprolol Impurity 17 (CAS 158553-31-2)
- Metoprolol Impurity 20 (CAS 18995-35-2)
- Metoprolol Impurity 26 (CAS 69628-98-4)
- Metoprolol Impurity 9 (CAS 1155083-53-6)
- Metoprolol Impurity 18 (CAS 56718-70-8)
- Metoprolol Impurity 29 (CAS 89507-60-8)
- Metoprolol Impurity 21 (CAS 84697-14-3)
- Metoprolol EP Impurity F (CAS 7695-63-8)
Recommended Standards
- Posaconazole Impurity 269 (CAS CATO-C4X-1208269)
- Itopride Impurity 3 (CAS 20059-73-8)
- Posaconazole impurity 243 (CAS CATO-C4X-1208243)
- Propofol Impurity 22 (CAS 1988-10-9)
- Cefditoren Impurity 32 (CAS CATO-C4X-135832)
- Canagliflozin Peroxide Impurity in CH3CN/H2O (CAS CATO-C4X-112333)
- Erlotinib Impurity 144 (CAS CATO-C4X-1069144)
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- Pancreatic Polypeptide (human) trifluoroacetate salt (CAS 75976-10-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com