Avatrombopag Impurity 70 CAS 19982-04-8
| CAS No. | 19982-04-8 |
| Molecular Formula | C16H30N2 |
| Molecular Weight | 250.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Avatrombopag Impurity 70 (CAS 19982-04-8, C16H30N2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Avatrombopag Impurity 70 (C16H30N2) contains a nitrile group. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 250.42 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H30N2 |
| Molecular Weight | 250.42 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1962 |
| Nitrogen Atoms | 2 |
Related Avatrombopag Standards
- Avatrombopag Impurity 26 (CAS 959042-70-7)
- Avatrombopag Impurity 84 (CAS CATO-C4X-223484)
- Avatrombopag Impurity 86 (CAS 81216-89-9)
- Avatrombopag Impurity 35 (CAS 677007-73-7)
- Avatrombopag Impurity 71 (CAS 252263-38-0)
- Avatrombopag Impurity 114 (CAS CATO-C4X-2234114)
- Avatrombopag Impurity 95 (CAS CATO-C4X-223495)
- Avatrombopag Impurity 51 (CAS CATO-C4X-223451)
Recommended Standards
- 22679-54-5 4-tert-Butylbenzophenone Methanone, (4-(1,1-dimethylethyl)phenyl)phenyl- EINECS 245-154-1 (CAS 22679-54-5)
- 1,3-Bis(trimethylsilyl)-1,3,2-diazaphosphinane 2-oxide (CAS 113107-36-1)
- (E)-4-(4-aminostyryl)-N,N-dimethylaniline 22525-43-5 4-Amino-4'-(N,N-dimethylamino)stilbene (CAS 22525-43-5)
- 2,3,4-Trichloro-6-(trifluoromethyl)pyridine (CAS 1214344-06-5)
- Brexpiprazole Impurity 46 (CAS 2454317-17-8)
- Rivaroxaban Impurity 162 (CAS 2197189-55-0)
- Trazodone Impurity 87 HBr (CAS CATO-C4X-177287)
- 1-(4-Bromo-2-(trifluoromethyl)phenyl)-4,4-difluoropiperidine (CAS 1779123-39-5)
- Retinoic Acid Related Compound 1 (CAS 40835-18-5)
- 6-Iodo-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one (CAS 1203499-25-5)
- 5-(tert-Butyl) 3-ethyl 6,7-dihydroisoxazolo[4,5-c]pyridine-3,5(4H)-dicarboxylate (CAS 912265-92-0)
- Methyl (2R,4S)-4-hydroxy-1-methylpyrrolidine-2-carboxylate (CAS 2206738-56-7)
- 1,3-Bis(trifluoromethyl)-5-fluorobenzene 1-fluoro-3,5-bis(trifluoromethyl)benzene 35564-19-3 alpha,alpha,alpha,alpha',alpha',alpha',5-Heptafluoro-m-xylene (CAS 35564-19-3)
- Hexapeptide-1 (CAS CATO-CPTD788821)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com