Trazodone Impurity 87 HBr CAS CATO-C4X-177287

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-177287
Molecular FormulaC13H18BrClN2
Molecular WeightN/A
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Trazodone Impurity 87 HBr CAS CATO-C4X-177287 chemical structure

Description

As a certified reference material (CRM), Trazodone Impurity 87 HBr meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Trazodone Impurity 87 HBr (CAS CATO-C4X-177287) is a certified pharmaceutical impurity reference standard with the molecular formula C13H18BrClN2HBr and a molecular weight of 398.57 g/mol.

The molecular framework of Trazodone Impurity 87 HBr (C13H18BrClN2HBr) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

Physical & Chemical Properties

Molecular FormulaC13H18BrClN2 HBr
Molecular Weight398.57 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentCl/Br-containing
Nitrogen Atoms2

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