Avatrombopag Impurity 86 CAS 81216-89-9
| CAS No. | 81216-89-9 |
| Molecular Formula | C7H5BrN2S2 |
| Molecular Weight | 261.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Avatrombopag Impurity 86 (CAS 81216-89-9, C7H5BrN2S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Avatrombopag Impurity 86 (C7H5BrN2S2) contains a nitrile group, sulfur-containing functionality, bromine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 261.16 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Avatrombopag Impurity 86 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H5BrN2S2 |
| Molecular Weight | 261.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Avatrombopag Standards
- Avatrombopag Impurity 71 (CAS 252263-38-0)
- Avatrombopag Impurity 114 (CAS CATO-C4X-2234114)
- Avatrombopag Impurity 67 (CAS 901314-75-8)
- Avatrombopag Impurity 52 (CAS 1224935-95-8)
- Avatrombopag Impurity 26 (CAS 959042-70-7)
- Avatrombopag Impurity 84 (CAS CATO-C4X-223484)
- Avatrombopag Impurity 70 (CAS 19982-04-8)
- Avatrombopag Impurity 96 (CAS CATO-C4X-223496)
Recommended Standards
- 20717-79-7 1-Bromo-2-naphtoic acid MFCD00021408 1-Bromo-2-naphthalenecarboxylic acid (CAS 20717-79-7)
- Ethyl methyl (4-nitrophenyl) phosphate (CAS 1021-47-2)
- Methyl 5-bromobicyclo[3.2.2]Nonane-1-carboxylate (CAS 942999-82-8)
- 2-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-2-amine (CAS 1075683-56-5)
- Benserazide Impurity 22 (CAS 13677-79-7)
- Timolol EP Impurity G (CAS 75202-36-7)
- Peptide Impurity 40 (CAS CATO-CPTD788840)
- 6-Chloro-N-(4-pyridinylmethyl)-2-pyridinamine (CAS 1220018-69-8)
- 1-Amino-4-(trifluoromethyl)cyclohexane-1-carboxylic acid (CAS 1344110-31-1)
- tert-Butyl 5-(5-amino-3-isopropyl-1h-pyrazol-1-yl)-1h-indazole-1-carboxylate (CAS 1020173-63-0)
- 3-Amino-4-fluoro-2,3-dihydro-1H-inden-1-ol (CAS 1267693-91-3)
- 5-(2-bromo-5-fluorophenoxy)pyrimidine-2,4-diamine (CAS 935534-20-6)
- 19816-88-7 A813965 N-(1,3-diphenylpropan-2-ylideneamino)-4-methyl-benzenesulfonamide N-(1,3-diphenylpropan-2-ylideneamino)-4-methylbenzenesulfonamide (CAS 19816-88-7)
- Semaglutide impurity 63 (CAS CATO-C4X-222663)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com