Avatrombopag Impurity 114 CAS CATO-C4X-2234114

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-2234114
Molecular FormulaC6H2Cl4OS
Molecular Weight263.96 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Avatrombopag Impurity 114 CAS CATO-C4X-2234114 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Avatrombopag Impurity 114.

CATO supplies Avatrombopag Impurity 114 (CAS CATO-C4X-2234114), a pharmacopoeial impurity reference standard (molecular formula C6H2Cl4OS, MW 263.96 g/mol) used for the identification and quantification of trace impurities in APIs.

Structurally, Avatrombopag Impurity 114 (C6H2Cl4OS) contains sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 263.96 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Avatrombopag Impurity 114 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC6H2Cl4OS
Molecular Weight263.96 g/mol
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentCl-containing
Sulfur Atoms1

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