Apixaban Impurity 28 CAS 503612-76-8
| CAS No. | 503612-76-8 |
| Molecular Formula | C24H23N5O4 |
| Molecular Weight | 445.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Apixaban Impurity 28 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Apixaban Impurity 28 (CAS 503612-76-8) is a certified pharmaceutical impurity reference standard with the molecular formula C24H23N5O4 and a molecular weight of 445.47 g/mol.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, Apixaban Impurity 28 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 445.47 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C24H23N5O4 |
| Molecular Weight | 445.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Nitrogen Atoms | 5 |
Related Apixaban Standards
- Apixaban Impurity 163 (CAS CATO-C4X-1088163)
- Apixaban Impurity 7 (CAS 1777781-49-3)
- Apixaban Impurity 58 (CAS CATO-C4X-108858)
- Apixaban Impurity 44 (CAS 536759-91-8)
- Apixaban Impurity 133 (CAS CATO-C4X-1088133)
- Apixaban Impurity 181 (CAS CATO-C4X-1088181)
- Apixaban Impurity 149 (CAS CATO-C4X-1088149)
- Apixaban Impurity 27 (CAS 1074549-89-5)
Recommended Standards
- N-(9-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)-2,2-diphenylacetamide (CAS 95900-44-0)
- Azilsartan impurity 140 (CAS CATO-C4X-1096140)
- Bis(tert-Butoxycarbonyl) Lisdexamphetamine (CAS 819871-13-1)
- Entacapone Impurity 5（Mixture of chiral isomers） (CAS CATO-C4X-16295)
- Levothyroxine N-Acetyl Impurity (CAS 26041-51-0)
- Ethosuximide impurity 12 (CAS CATO-C4X-262512)
- N-Nitroso Pseudoephedrine (N-Nitroso Ephedrine HCl EP Impurity B) (CAS 1850-88-0)
- Ethyl 3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxylate hydrochloride (CAS 13582-92-8)
- 5-(1-Amino-2-methoxyethyl)-2-fluorophenol (CAS 1270368-91-6)
- 4-(3,4-Difluorophenyl)butanoic acid (CAS 136295-00-6)
- 1-(1,2-dimethyl-1H-imidazol-4-yl)ethan-1-one (CAS 103747-86-0)
- (E)-N'-Benzylidene-2-(4-chlorophenoxy)acetohydrazide (CAS 1351480-52-8)
- 5-(3-Chloro-4-methylphenyl)furan-2-carbaldehyde (CAS 57666-53-2)
- Semaglutide impurity 106 (CAS CATO-C4X-2226106)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com