Tocopherol impurity 38 CAS 2011-58-7
| CAS No. | 2011-58-7 |
| Molecular Formula | C9H11ClO2 |
| Molecular Weight | 186.64 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Tocopherol impurity 38 is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Tocopherol impurity 38 (CAS 2011-58-7) is a certified pharmaceutical impurity reference standard with the molecular formula C9H11ClO2 and a molecular weight of 186.64 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Tocopherol impurity 38 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 186.64 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Tocopherol impurity 38 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H11ClO2 |
| Molecular Weight | 186.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
Related Tocopherol Standards
- Tocopherol impurity 39 (CAS 51028-70-7)
- alpha-Tocopherol Phosphate Disodium Salt (CAS 90940-45-7)
- α-Tocopherol phosphate disodium (CAS 60934-46-5)
- Tocopherol Impurity 41 (CAS 389845-92-5)
- (+)-Δ-Tocopherol (CAS 119-13-1)
- alpha-Tocopherol quinone (CAS 62726-91-4)
- Tocopherol (CAS 1406-66-2)
- Beta-Tocopherol (CAS 148-03-8)
Recommended Standards
- 2-(Chloromethyl)-1,4-dimethoxybenzene (CAS 3840-27-5)
- Losartan EP Impurity D (CAS 83857-96-9)
- 915922-38-2 (3-Chloro-4-ethoxyphenyl)methanol DTXSID90598300 (CAS 915922-38-2)
- Verapamil Impurity 25 (CAS 3893-01-4)
- Enarodustat Impurity 12 (CAS CATO-C4X-322812)
- Faropenem Impurity 47 (CAS 76899-07-5)
- Avatrombopag Impurity 118 (CAS CATO-C4X-2234118)
- 2-(Trifluoromethoxy)pyridin-4-amine dihydrochloride (CAS 1707713-95-8)
- 7-Amino-2,3-dimethyl-5-(methylthio)pyrazolo[1,5-a]pyrimidine-6-carbonitrile (CAS 2798825-79-1)
- Atorvastatin impurity 160 (CAS 1112262-76-6)
- 2-Oxo-2-(p-tolyl)ethyl 2-hydroxybenzoate (CAS 324066-07-1)
- meso-Tetraphenylporphyrin (CAS 917-23-7)
- 2-Methoxy-4-(prop-2-yn-1-yloxy)benzoic acid (CAS 85607-70-1)
- Osteoblast Activating Peptide (mouse, rat) (H-7262.0500) (CAS 1222950-80-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com