Losartan EP Impurity D CAS 83857-96-9
| CAS No. | 83857-96-9 |
| Molecular Formula | C8H11ClN2O |
| Molecular Weight | 186.64 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Losartan EP Impurity D (C8H11ClN2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Losartan EP Impurity D (CAS 83857-96-9) is a certified pharmaceutical impurity reference standard with the molecular formula C8H11ClN2O and a molecular weight of 186.64 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Losartan EP Impurity D under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H11ClN2O |
| Molecular Weight | 186.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Losartan Standards
- Losartan Impurity 1 (CAS 79047-41-9)
- Losartan Impurity 20 (CAS 154709-19-0)
- Losartan Impurity 63 (CAS CATO-C4X-168363)
- Losartan Impurity 18 (CAS 158365-99-2)
- Losartan Impurity 23 (CAS 193140-43-1)
- Losartan Potassium EP Impurity E (CAS 120568-11-8)
- Losartan EP Impurity B (CAS 160514-13-6)
- Losartan Impurity 59 (CAS 57246-71-6)
Recommended Standards
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- Verapamil Impurity 27 (CAS 7306-46-9)
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- CAS 230615-12-0 (CAS 230615-12-0)
- Edoxaban impurity 135 (CAS 852291-42-0)
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- 5-Bromo-3-cyclopropyl-1,2,4-thiadiazole (CAS 1494127-23-9)
- 1-((4-Bromophenoxy)methyl)-2-methylbenzene (CAS 856381-92-5)
- 1,6-Anhydro-2,3,4-tri-O-benzyl-β-D-glucopyranose (CAS 10548-46-6)
- 3-(Dimethylamino)-1-ethyl-2,3-dihydroquinazoline-4(1H)-thione (CAS 90070-37-4)
- 1-(4-Bromo-2-chlorobenzyl)-1H-pyrazol-4-ol (CAS 1593966-28-9)
- ((Cys31,Nva34)-Neuropeptide Y (27-36))2 (CAS 172997-92-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com