Sildenafil Impurity 76 CAS CATO-C4X-112876
| CAS No. | CATO-C4X-112876 |
| Molecular Formula | C18H22N4O4S |
| Molecular Weight | 390.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Sildenafil Impurity 76.
CATO supplies Sildenafil Impurity 76 (CAS CATO-C4X-112876), a pharmacopoeial impurity reference standard (molecular formula C18H22N4O4S, MW 390.46 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C18H22N4O4S, Sildenafil Impurity 76 contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 390.46 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Sildenafil Impurity 76 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H22N4O4S |
| Molecular Weight | 390.46 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Sildenafil Standards
- Sildenafil Impurity 45 (CAS 1391054-00-4)
- Sildenafil Impurity 27 (CAS 372089-76-4)
- Sildenafil Impurity 5 (CAS 1058653-74-9)
- Sildenafil EP Impurity D (CAS 1357931-55-5)
- Sildenafil Impurity 9 (CAS 139756-31-3)
- Sildenafil Impurity 8 (CAS 139756-27-7)
- Sildenafil Impurity 261 (CAS CATO-C4X-1128261)
- Sildenafil Impurity 52 (CAS CATO-C4X-112852)
Recommended Standards
- N-(Benzo[d][1,3]dioxol-5-ylmethyl)-5,6-dimethyl-2-(pyridin-3-yl)thieno[2,3-d]pyrimidin-4-amine (CAS 796052-04-5)
- Lubiprostone (CAS 136790-76-6/333963-40-9)
- N-(5-Cyclopropyl-1,3,4-oxadiazol-2-yl)-4-((2-methylpiperidin-1-yl)sulfonyl)benzamide (CAS 850935-88-5)
- Lubiprostone Impurity 18 (CAS 201226-21-3)
- Formoterol impurity 128 (CAS CATO-C4X-1525128)
- Imrecoxib Impurity 38 (CAS 2268704-43-2)
- Etoposide Impurity 37 (CAS CATO-C4X-202437)
- Methyl 2-Amino-2-(3,4-dichlorophenyl)acetate Hydrochloride (CAS 1078611-21-8)
- 8-Methylnonyl nonanoate (CAS 109-32-0)
- 4-(3-Methoxyphenyl)-2-pyrimidinamine (CAS 1158235-36-9)
- 2-Chloro-6-ethynylpyridine (CAS 914950-09-7)
- (2,3-Difluoro-6-iodophenyl)methanol (CAS 887585-77-5)
- 1-(1H-imidazol-1-yl)butan-2-amine (CAS 844882-20-8)
- Pheromone Biosynthesis Activating Neuropeptide (Helicoverpa assulta, Heliothis zea) (CAS 122071-54-9)
Why CATO?
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