Leflunomide Impurity 21 CAS 202057-74-7
| CAS No. | 202057-74-7 |
| Molecular Formula | C12H9N3O2 |
| Molecular Weight | 227.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Leflunomide Impurity 21 (CAS 202057-74-7) is a certified pharmaceutical impurity reference standard with the molecular formula C12H9N3O2 and a molecular weight of 227.22 g/mol.
Based on its molecular formula C12H9N3O2, Leflunomide Impurity 21 contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 227.22 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Leflunomide Impurity 21 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H9N3O2 |
| Molecular Weight | 227.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2014 |
| Nitrogen Atoms | 3 |
Related Leflunomide Standards
- Leflunomide EP Impurity H (CAS 24522-30-3)
- Leflunomide Impurity 25 (CAS CATO-C4X-167325)
- Leflunomide EP Impurity G (CAS 724429-16-7)
- Leflunomide Impurity 2 (CAS 827029-20-9)
- Leflunomide Impurity 14 (CAS 51145-57-4)
- Leflunomide (CAS 75706-12-6)
- Leflunomide EP Impurity C (CAS 61643-23-0)
- Leflunomide EP Impurity E (CAS 208401-20-1)
Recommended Standards
- Doxofylline Impurity 10 (CAS CATO-C4X-151310)
- Urapidil Impurity 44 (CAS CATO-C4X-192444)
- Benserazide impurity 41 (CAS 28311-19-5)
- Dorzagliatin Impurity 10 (CAS CATO-C4X-344110)
- Dyclonine Impurity 20 (CAS 35999-21-4)
- Cetirizine EP Impurity D DiHCl (CAS 856841-95-7)
- Empagliflozin impurity 225 (CAS CATO-C4X-1065225)
- 6-Isopropylindoline (CAS 122299-59-6)
- 1-methyl-5-(phenoxymethyl)-1H-pyrazol-3-amine (CAS 1354704-34-9)
- 6-Bromo-2-(trifluoromethyl)imidazo[2,1-b]thiazole (CAS 1956379-60-4)
- Cefotetan Sodium (CAS 74356-00-6)
- Methyl 2-(((5R,6S,9S)-5-benzyl-1-(9H-fluoren-9-yl)-6-hydroxy-9-isobutyl-3,7,10,22-tetraoxo-2,14,17,20-tetraoxa-4,8,11,23-tetraazahexacosan-26-yl)oxy)-4-((E)-3-(3,5-di-tert-butylphenyl)-3-oxoprop-1-en-1-yl)benzoate (CAS 1351169-42-0)
- 4-(Azetidin-3-yl)-2,6-dichloropyridine (CAS 1260869-26-8)
- Liraglutide Impurity 30 (CAS CATO-C4X-199230)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com