Bevantolol impurity 2 CAS 204584-12-3
| CAS No. | 204584-12-3 |
| Molecular Formula | C12H16O4 |
| Molecular Weight | 224.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Bevantolol impurity 2 (CAS 204584-12-3) is a certified pharmaceutical impurity reference standard with the molecular formula C12H16O4 and a molecular weight of 224.25 g/mol.
The molecular framework of Bevantolol impurity 2 (C12H16O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Bevantolol impurity 2 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H16O4 |
| Molecular Weight | 224.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2015 |
Related Bevantolol Standards
- Bevantolol Impurity 5 (CAS 147220-24-4)
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- Bevantolol Impurity 24 (CAS CATO-C4X-241124)
- Bevantolol Impurity 14 (CAS 621-24-9)
- Bevantolol impurity 3 (CAS 15620-78-7)
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Recommended Standards
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- Lurasidone Impurity 37 (CAS CATO-C4X-102837)
- Axitinib impurity 46 (CAS 261953-36-0)
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- 1,3-Dimethyl 5-[4-(1h-pyrazol-1-yl)benzamido]benzene-1,3-dicarboxylate (CAS 1185017-23-5)
- Tolvaptan Impurity 123 (CAS CATO-C4X-1955123)
- tert-Butyl 2-methyl-4-nitrobenzoate (CAS 62621-12-9)
- [2-31]-Semaglutide C (x TFA Salt) (CAS CATO-C4X-2226118)
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