Asarone Impurity 1 CAS 3904-18-5
| CAS No. | 3904-18-5 |
| Molecular Formula | C12H16O4 |
| Molecular Weight | 224.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Asarone Impurity 1.
Asarone Impurity 1 (CAS 3904-18-5) is a certified pharmaceutical impurity reference standard with the molecular formula C12H16O4 and a molecular weight of 224.25 g/mol.
The molecular framework of Asarone Impurity 1 (C12H16O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Asarone Impurity 1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H16O4 |
| Molecular Weight | 224.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
Related Asarone Standards
Recommended Standards
- Olopatadine Impurity 46 (CAS 23560-66-9)
- Bevantolol impurity 2 (CAS 204584-12-3)
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- Bevantolol Impurity 5 (CAS 147220-24-4)
- Daclatasvir Impurity 13 (CAS CATO-C4X-184813)
- Lamivudine Impurity 20 (CAS CATO-C4X-119420)
- Aficamten Impurity 3 (CAS CATO-C4X-34803)
- Ethyl 2-amino-1H-indole-6-carboxylate (CAS 412284-12-9)
- 2-(3,5-Bis(trifluoromethyl)phenyl)acetaldehyde (CAS 369625-84-3)
- N-(4-(4-(sec-butyl)phenyl)thiazol-2-yl)acetamide (CAS 478065-86-0)
- 2,4-Difluoro-5-(trifluoromethyl)benzoic acid (CAS 261945-01-1)
- Dydrogesterone Impurity 1 (CAS 1819-14-3)
- 6-Ethyl-2-(Hydroxymethyl)pyrimidin-4-ol (CAS 1263214-00-1)
- Peptide Impurity 82 (CAS 10491-78-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com