Ketorolac Impurity 18 CAS CATO-C4X-166918
| CAS No. | CATO-C4X-166918 |
| Molecular Formula | C8H20N2O5 |
| Molecular Weight | 224.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 224.25 g/mol gives Ketorolac Impurity 18 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Ketorolac Impurity 18 (CAS CATO-C4X-166918, C8H20N2O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Ketorolac Impurity 18 (C8H20N2O5) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Ketorolac Impurity 18 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H20N2O5 |
| Molecular Weight | 224.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 0.0 |
| Nitrogen Atoms | 2 |
Related Ketorolac Standards
- Ketorolac EP Impurity B (CAS 113502-52-6)
- Ketorolac Impurity 19 (CAS CATO-C4X-166919)
- Ketorolac EP Impurity A (CAS 154476-25-2)
- Ketorolac impurity 62 (CAS 141054-46-8)
- Ketorolac Impurity 39 (CAS CATO-C4X-166939)
- Ketorolac impurity 01 (CAS 87549-01-7)
- Ketorolac Impurity 48 (CAS CATO-C4X-166948)
- Ketorolac EP Impurity I (CAS 113502-55-9)
Recommended Standards
- Clomifene Impurity 8 (CAS 23464-17-7)
- Olopatadine Impurity 46 (CAS 23560-66-9)
- Loxoprofen impurity 121 (CAS CATO-C4X-1488121)
- Asarone Impurity 1 (CAS 3904-18-5)
- Furosemide Impurity 57 (CAS 19377-82-3)
- Acetylcysteine Impurity 20 (CAS CATO-C4X-153220)
- Clopidogrel EP Impurity E (R-Isomer) (CAS 444728-15-8)
- 3-(3-(Trifluoromethyl)phenoxy)propanenitrile (CAS 1019120-01-4)
- 2-Bromo-N-((R)-1-phenylethyl)butanamide (CAS 1344972-53-7)
- (R)-1-(3-Methoxy-2-methylphenyl)propan-2-amine (CAS 1336462-27-1)
- 6285-57-0 4321510DG9 2-Amino-6-nitrobenzothiazole 2-Benzothiazolamine, 6-nitro- Benzothiazole, 2-amino-6-nitro- (8CI) 6-Nitrobenzothiazol-2-amine 4-27-00-04876 (Beilstein Handbook Reference) BRN 0177844 CCRIS 1391 EINECS 228-513-7 6-Nitro-2-aminobenzothiazole 6-Nitro-2-benzothiazolamine NSC 10794 NSC 62341 NSC 62980 UNII-4321510DG9 (CAS 6285-57-0)
- (E)-N-(4-Chlorophenyl)-3-methoxy-N'-methylbenzene-1-carboximidamide (CAS 303149-36-2)
- 1-(5-(Furan-2-yl)isoxazol-3-yl)cyclopropanecarboxylic acid (CAS 1352506-26-3)
- Atrial Natriuretic Peptide (ANP)(1-28) Alpha (Human, Ovine, Canine) (CAS 91917-63-4)
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