Lifitegrast Impurity 26 CAS 2049127-86-6
| CAS No. | 2049127-86-6 |
| Molecular Formula | C10H13NO4S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Lifitegrast Impurity 26 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Lifitegrast Impurity 26 (CAS 2049127-86-6, C10H13NO4SHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C10H13NO4SHCl, Lifitegrast Impurity 26 contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 279.74 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C10H13NO4S HCl |
| Molecular Weight | 279.74 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Lifitegrast Standards
- Lifitegrast (CAS 1025967-78-5)
- Lifitegrast Impurity 37 (CAS 1194550-56-5)
- Lifitegrast Impurity 49 (CAS 1194550-59-8)
- Lifitegrast Impurity 30 (CAS 1194550-61-2)
- Lifitegrast Impurity 23 (CAS 1194550-65-6)
- Lifitegrast Impurity 11 (CAS 1194550-67-8)
- Lifitegrast Impurity 39 (CAS 1194864-16-8)
- Lifitegrast Impurity N99 (CAS 1195655-47-0)
Recommended Standards
- Rocuronium Bromide EP Impurity H (CAS 1190105-67-9)
- Empagliflozin Impurity 290 (CAS CATO-C4X-1065290)
- Anagrelide Impurity 44 (CAS 183620-20-4)
- 1-(5,7-Dibromobenzofuran-2-yl)ethan-1-one (CAS 7203-79-4)
- 4,4',5,5'-Tetra(pyridin-3-yl)-2,2'-bi(1,3-dithiolylidene) (CAS 1356336-68-9)
- (4-(Trifluoromethyl)benzyl)hydrazine hydrochloride (CAS 74195-71-4)
- (4S)-3,8-Dibromo-4H,9H-dipyrazolo[1,5-a:1',5'-d]pyrazine-4,9-diol (CAS 1212466-82-4)
- 3-Amino-1,1,1-trifluoropropan-2-one hydrochloride (CAS 1260812-54-1)
- SYH2092A-013208 (CAS CATO-CPTD788848)
- Semaglutide Impurity 18 (CAS 1671100-14-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com