Ethyl 4-chloro-6-(trifluoromethoxy)quinoline-3-carboxylate CAS 207231-23-0
| CAS No. | 207231-23-0 |
| Molecular Formula | C13H9ClF3NO3 |
| Molecular Weight | 319.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Ethyl 4-chloro-6-(trifluoromethoxy)quinoline-3-carboxylate (CAS 207231-23-0), molecular formula C13H9ClF3NO3 and molecular weight 319.66 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, Ethyl 4-chloro-6-(trifluoromethoxy)quinoline-3-carboxylate (C13H9ClF3NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 319.66 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Ethyl 4-chloro-6-(trifluoromethoxy)quinoline-3-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H9ClF3NO3 |
| Molecular Weight | 319.66 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2016 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- Ethyl 4-chloro-8-(trifluoromethoxy)quinoline-3-carboxylate (CAS 1040013-63-5)
- Ethyl 8-chloro-4-hydroxy-6-(trifluoromethyl)quinoline-3-carboxylate (CAS 1065094-20-3)
- Ethyl 6-chloro-4-hydroxy-8-(trifluoromethyl)quinoline-3-carboxylate (CAS 1065102-34-2)
- Ethyl 5-chloro-4-hydroxy-8-(trifluoromethyl)quinoline-3-carboxylate (CAS 1065102-35-3)
- Ethyl 8-chloro-4-hydroxy-5-(trifluoromethyl)quinoline-3-carboxylate (CAS 1221573-17-6)
- Methyl 4-chloro-6-methoxy-2-(trifluoromethyl)quinoline-3-carboxylate (CAS 1384264-19-0)
- Ethyl 4-chloro-7-(trifluoromethoxy)quinoline-3-carboxylate (CAS 890841-23-3)
- Ethyl 6-chloro-4-hydroxy-7-(trifluoromethyl)quinoline-3-carboxylate (CAS 958332-77-9)
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