Ethyl 4-chloro-6,7,8-trifluoroquinoline-3-carboxylate CAS 207231-24-1
| CAS No. | 207231-24-1 |
| Molecular Formula | C12H7ClF3NO2 |
| Molecular Weight | 289.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 4-chloro-6,7,8-trifluoroquinoline-3-carboxylate.
Ethyl 4-chloro-6,7,8-trifluoroquinoline-3-carboxylate (CAS 207231-24-1) is a high-purity analytical reference standard with the molecular formula C12H7ClF3NO2 and a molecular weight of 289.64 g/mol.
The molecular framework of Ethyl 4-chloro-6,7,8-trifluoroquinoline-3-carboxylate (C12H7ClF3NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Ethyl 4-chloro-6,7,8-trifluoroquinoline-3-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H7ClF3NO2 |
| Molecular Weight | 289.64 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2016 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- Methyl 4-chloro-8-(trifluoromethyl)quinoline-2-carboxylate (CAS 1133115-62-4)
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Recommended Standards
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- Methyl 4-chloro-2-(trifluoromethyl)quinoline-6-carboxylate (CAS 958332-63-3)
- 447438-06-4 5-Chloro-2-methoxy-4-[(trifluoroacetyl)amino]benzoic Acid Methyl Ester Methyl 5-Chloro-2-methoxy-4-trifluoroacetamidobenzoate (CAS 447438-06-4)
- 4-(chloromethyl)-2-(4-methanesulfonylphenyl)-1,3-oxazole (CAS 1178081-96-3)
- 1-(5-benzyl-1,2,4-oxadiazol-3-yl)ethan-1-amine hydrochloride (CAS 1376344-63-6)
- 4-(Difluoromethyl)-3-methoxy-6-(trifluoromethoxy)pyridin-2-ol (CAS 1803695-86-4)
- 2-Chloro-N-[3-cyano-1-(3-fluorophenyl)-4,5-dimethyl-1h-pyrrol-2-yl]acetamide (CAS 852399-61-2)
- tert-Butyl 4-(aminomethyl)-4-(cyclobutylmethyl)piperidine-1-carboxylate (CAS 1779132-53-4)
- ethyl 4-(N,N-diethylamino)benzoate (CAS 10287-54-4)
- Ethyl 2-(2-iodoethoxy)acetate (CAS 56703-25-4)
- Dioctadecyl 3,3＇-Thiodipropionate (CAS 693-36-7)
- (Thr(PO3H2)231)-Tau Peptide (225-237) trifluoroacetate salt (CAS 1670270-09-3)
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