Verapamil EP Impurity P CAS 2086275-13-8
| CAS No. | 2086275-13-8 |
| Molecular Formula | C29H38N2O4 |
| Molecular Weight | 478.62 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Verapamil EP Impurity P (C29H38N2O4) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Verapamil EP Impurity P (CAS 2086275-13-8) is a certified pharmaceutical impurity reference standard with the molecular formula C29H38N2O4 and a molecular weight of 478.62 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Verapamil EP Impurity P meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C29H38N2O4 |
| Molecular Weight | 478.62 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Nitrogen Atoms | 2 |
Related Verapamil Standards
- Verapamil EP Impurity J HCl (CAS 67812-42-4)
- (R)-Verapamil-D6 (isopropyl-1,1,1,3,3,3-D6) (CAS 1796641-49-0)
- Verapamil Impurity 43 (CAS 94219-84-8)
- Verapamil Impurity 34 (CAS CATO-C4X-177834)
- (R)-(+)-Verapamil HCl (CAS 38321-02-7)
- Verapamil EP Impurity O (CAS 959011-16-6)
- Verapamil (CAS 52-53-9)
- Verapamil EP Impurity H (CAS 67018-83-1)
Recommended Standards
- 2082752-83-6 X150A3JK8R Aclimostat UNII-X150A3JK8R Aclimostat [INN] (3R,4S,5S,6R)-5-Methoxy-4-((2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl)-1-oxaspiro(2.5)octan-6-yl 3-(2-(morpholin-4-yl)ethyl)azetidine-1-carboxylate ZGN-1061 1-Azetidinecarboxylic acid, 3-(2-(4-morpholinyl)ethyl)-, (3R,4S,5S,6R)-5-methoxy-4-((2R,3R)-2-methyl-3-(3-methyl-2-buten-1-yl)-2-oxiranyl)-1-oxaspiro(2.5)oct-6-yl ester (3R,4S,5S,6R)5Methoxy4((2R,3R)2methyl3(3methylbut2en1yl)oxiran2yl)1oxaspiro(2.5)octan6yl 3(2(morpholin4yl)ethyl)azetidine1carboxylate (CAS 2082752-83-6)
- N-(2-(2-((Dipropylamino)methyl)piperidin-1-yl)ethyl)-6-oxo-5H-benzo[e]pyrido[3,2-b][1,4]diazepine-11(6H)-carboxamide (CAS 118290-26-9)
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- 3-(Pyrrolidin-2-yl)quinoline (CAS 499207-38-4)
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