Apremilast Impurity 101 CAS 208774-55-4
| CAS No. | 208774-55-4 |
| Molecular Formula | C10H11NO4 |
| Molecular Weight | 209.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Apremilast Impurity 101 (CAS 208774-55-4, C10H11NO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Apremilast Impurity 101 (C10H11NO4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Apremilast Impurity 101 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H11NO4 |
| Molecular Weight | 209.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2016 |
| Nitrogen Atoms | 1 |
Related Apremilast Standards
- Apremilast Impurity 102 (CAS 1822756-03-5)
- Apremilast Impurity 71 (CAS CATO-C4X-100971)
- Apremilast Impurity 107 (CAS 22235-04-7)
- Apremilast Impurity 42 (CAS 6296-53-3)
- Apremilast Impurity 98 (CAS CATO-C4X-100998)
- Apremilast Impurity 87 (CAS 202262-76-8)
- Apremilast Impurity N7 (CAS 2651-55-0)
- Apremilast Impurity 112 (CAS 247569-89-7)
Recommended Standards
- 2-(4-Formyl-2-methoxyphenoxy)acetamide (CAS 186685-89-2)
- 54231-37-7 Morpholine, 4-(2-nitro-3-pyridinyl)- (CAS 54231-37-7)
- Metoclopramide Impurity 24 (CAS 55304-05-7)
- 2-Methoxy-4-(2-nitro-1-propenyl)phenol 2-Methoxy-4-(2-nitropropenyl)phenol 5395-47-1 NSC 3298 NSC 57759 (CAS 5395-47-1)
- Ixazomib Impurity 62 (CAS CATO-C4X-126762)
- Testosterone Propionate EP Impurity E (CAS 25862-97-9)
- Zanamivir Impurity 11 (CAS CATO-C4X-205011)
- 3-(P-tolyl)quinolin-2-amine (CAS 33543-53-2)
- 4-Phenyl-3-(trifluoromethyl)pyridine (CAS 1803844-39-4)
- 1-(3-Methylbutyl)-5-(propan-2-yl)-1h-pyrazole-4-carboxylic acid (CAS 1250386-38-9)
- Elagolix Impurity 18 (CAS 117049-14-6)
- 6-Bromobenzo[d][1,3]dioxol-5-ol (CAS 6941-70-4)
- Phenylephrine Impurity 24 (CAS CATO-C4X-146724)
- Peptide T (CAS 106362-32-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com