Apremilast Impurity 98 CAS CATO-C4X-100998
| CAS No. | CATO-C4X-100998 |
| Molecular Formula | C7H2F3N3O |
| Molecular Weight | 201.11 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Apremilast Impurity 98 (CAS CATO-C4X-100998) is a certified pharmaceutical impurity reference standard with the molecular formula C7H2F3N3O and a molecular weight of 201.11 g/mol.
The molecular framework of Apremilast Impurity 98 (C7H2F3N3O) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H2F3N3O |
| Molecular Weight | 201.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Apremilast Standards
- Apremilast Impurity 87 (CAS 202262-76-8)
- Apremilast Impurity 107 (CAS 22235-04-7)
- Apremilast Impurity 42 (CAS 6296-53-3)
- Apremilast Impurity N7 (CAS 2651-55-0)
- Apremilast Impurity 112 (CAS 247569-89-7)
- Apremilast Impurity 34 (CAS CATO-C4X-100934)
- Apremilast Impurity 47 (CAS 1956-36-1)
- Apremilast impurity 96 (CAS 856806-92-3)
Recommended Standards
- 5-Fluoro-2,4-dinitroaniline (CAS 367-81-7)
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- 3,5-dichloro-2-(methylthio)pyrazine (CAS 1523571-95-0)
- Lodoxamide lmpurity 12 (CAS 69236-82-4)
- Roflumilast Impurity 30 (CAS 34809-82-0)
- Pipotiazine Impurity 1 (CAS CATO-C4X-33611)
- (S)-2-(3-methoxyphenyl)-2-(methylamino)ethan-1-ol (CAS 1213522-83-8)
- 2145-27-9 7-Fluoro-4-hydroxy-1(2H)-benzopyran-2-one 7-Fluoro-4-hydroxy-2H-chromen-2-one 7-Fluoro-4-hydroxycoumarin (CAS 2145-27-9)
- 4-Bromo-2-(2-methoxypyridin-3-yl)thiazole (CAS 1415562-60-5)
- Levonordefrin (200 mg) (CAS 829-74-3)
- N-cyclohexyl-2-(2-(thiophen-2-yl)acetyl)hydrazine-1-carboxamide (CAS 904824-98-2)
- 6-Bromo-2-chloroquinazoline (CAS 882672-05-1)
- Peptide YY (3-36) (human) (CAS 123583-37-9)
Why CATO?
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