4-Chloro-5-(difluoromethyl)-7H-pyrrolo[2,3-d]pyrimidine CAS 2090261-97-3

Purity 97%+In StockPharmaceutical Standards
CAS No.2090261-97-3
Molecular FormulaC7H4ClF2N3
Molecular Weight203.58 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Chloro-5-(difluoromethyl)-7H-pyrrolo[2,3-d]pyrimidine CAS 2090261-97-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 203.58 g/mol gives 4-Chloro-5-(difluoromethyl)-7H-pyrrolo[2,3-d]pyrimidine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

4-Chloro-5-(difluoromethyl)-7H-pyrrolo[2,3-d]pyrimidine (CAS 2090261-97-3), molecular formula C7H4ClF2N3 and molecular weight 203.58 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 4-Chloro-5-(difluoromethyl)-7H-pyrrolo[2,3-d]pyrimidine (C7H4ClF2N3) is characterized by a nitrile group, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

CATO manufactures 4-Chloro-5-(difluoromethyl)-7H-pyrrolo[2,3-d]pyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC7H4ClF2N3
Molecular Weight203.58 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1997
Halogen ContentF/Cl-containing
Nitrogen Atoms3

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