Eplerenone EP Impurity D CAS 209253-82-7
| CAS No. | 209253-82-7 |
| Molecular Formula | C23H28O6 |
| Molecular Weight | 400.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Eplerenone EP Impurity D (CAS 209253-82-7) is a certified pharmaceutical impurity reference standard with the molecular formula C23H28O6 and a molecular weight of 400.46 g/mol.
Structurally, Eplerenone EP Impurity D (C23H28O6) contains a flavonoid core, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 400.46 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C23H28O6 |
| Molecular Weight | 400.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2016 |
Related Eplerenone Standards
- Eplerenone EP Impurity G (CAS 41020-65-9)
- Eplerenone Impurity 11 (CAS 192704-70-4)
- Eplerenone EP Impurity C (CAS 95716-70-4)
- Eplerenone Impurity N1 (CAS 209253-72-5)
- Eplerenone Impurity 23 (CAS CATO-C4X-163023)
- Eplerenone Impurity 39 (CAS CATO-C4X-163039)
- Eplerenone Impurity 43 (CAS CATO-C4X-163043)
- Eplerenone 395665-48-2 (CAS 395665-48-2)
Recommended Standards
- Budesonide Impurity 36 (CAS 77017-20-0)
- Prednisone Impurity 9 (CAS 2435-02-1)
- Emtricitabine Impurity 59 (CAS 1422361-25-8)
- Prednisolone Impurity 28 (CAS 95440-71-4)
- Nintedanib Impurity 12 (CAS 2218446-42-3)
- Ozagrel Impurity 33 (CAS 946-99-6)
- Atrasentan Impurity 81 (CAS 1058552-23-0)
- (E)-2-Methylbut-2-enenitrile (CAS 30574-97-1)
- 2-((4-Chloro-2,5-dimethoxyphenyl)sulfonyl)-1,2,3,4-tetrahydroisoquinoline (CAS 700851-57-6)
- 2-((5-(4-(tert-Butyl)phenyl)-4-methyl-4H-1,2,4-triazol-3-yl)thio)-N-hydroxyacetimidamide (CAS 261704-26-1)
- Allyl 3-amino-3-(hydroxymethyl)pyrrolidine-1-carboxylate (CAS 951625-99-3)
- [4-(4-Methylphenoxy)-3-nitrophenyl]methyl 4-chlorobenzoate (CAS 338960-81-9)
- 4-Bromo-6-(difluoromethyl)-5-nitronicotinonitrile (CAS 1805368-97-1)
- Serpent Peptide (CAS 823202-99-9)
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