8-Fluoro-6-methoxyquinoline CAS 209353-21-9
| CAS No. | 209353-21-9 |
| Molecular Formula | C10H8FNO |
| Molecular Weight | 177.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 177.18 g/mol gives 8-Fluoro-6-methoxyquinoline distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
8-Fluoro-6-methoxyquinoline (CAS 209353-21-9) is a high-purity analytical reference standard with the molecular formula C10H8FNO and a molecular weight of 177.18 g/mol.
Based on its molecular formula C10H8FNO, 8-Fluoro-6-methoxyquinoline contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 177.18 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 8-Fluoro-6-methoxyquinoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H8FNO |
| Molecular Weight | 177.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2016 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 8-Fluoro-5-methoxyquinoline (CAS 887769-93-9)
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- 8-Fluoro-4-methylquinolin-2-ol (CAS 5279-86-7)
- Methyl 2-(cyanomethanesulfonyl)acetate (CAS 214691-87-9)
- 5-Bromo-2,6-dimethyl-1H-pyrrolo[2,3-b]pyridine (CAS 1427501-77-6)
- 2-Chloro-4-(dimethylphosphinyl)-6-(trifluoromethyl)pyridine (CAS 2680543-09-1)
- 3-(2-Iodobenzyl)oxetane (CAS 1823364-22-2)
- 3-Ethyl-4-(4-fluorophenyl)-1-methyl-1H-pyrazol-5-amine (CAS 956268-27-2)
- tert-Butyl 4-(6-(trifluoromethyl)pyridin-3-yl)piperazine-1-carboxylate (CAS 1229627-83-1)
- 4-(3-Bromopropyl)phenol (CAS 52273-55-9)
- Betamethasone-d5 (CAS CATO-CCAD301382)
- Ethyl 2-[(but-3-en-1-yl)amino]acetate (CAS 455333-83-2)
- 2-Amino-N-ethylbutyramide (CAS 1218474-73-7)
- Semaglutide impurity 34 (CAS CATO-C4X-222634)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com