Betamethasone-d5 CAS CATO-CCAD301382
| CAS No. | CATO-CCAD301382 |
| Molecular Formula | - |
| Molecular Weight | 397.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 397.49 g/mol gives Betamethasone-d5 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Betamethasone-d5 (CAS CATO-CCAD301382), molecular formula C22H24D5FO5 and molecular weight 397.49 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Betamethasone-d5 (C22H24D5FO5) is characterized by deuterium isotope labeling, a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H24D5FO5 |
| Molecular Weight | 397.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Betamethasone Standards
- Betamethasone Impurity N1 (CAS 910-99-6)
- Betamethasone Impurity 112 (CAS CATO-C4X-1437112)
- Betamethasone Impurity 121 (CAS CATO-C4X-1437121)
- Betamethasone Impurity 122 (CAS CATO-C4X-1437122)
- Betamethasone Impurity 89 (CAS CATO-C4X-143789)
- Betamethasone Impurity 86 (CAS 560-34-9)
- Betamethasone Impurity 136 (CAS CATO-C4X-1437136)
- Betamethasone Impurity 38 (CAS 25121-04-4)
Recommended Standards
- Dexamethasone-d5 (CAS 358731-91-6)
- NH-bis(m-PEG4) (CAS 123852-08-4)
- Brinzolamide Impurity 27 (CAS CATO-C4X-194027)
- 2-(2,2-Bis(ethylthio)acetyl)-N-(3-(trifluoromethyl)phenyl)hydrazine-1-carbothioamide (CAS 338394-35-7)
- 2-(Quinolin-8-ylazo)-4,5-diphenyl-1H-imidazole (CAS 4948-87-2)
- 4-Methyl-2-biphenylcarbonyl Chloride (CAS 854235-81-7)
- 3-(2-Hydroxyethyl)tetrahydrofuran-3-carboxylic acid (CAS 1508378-26-4)
- 4-[4-(Methoxycarbonyl)-2-methylphenyl]benzoic acid (CAS 170229-81-9)
- 2-(2-Chlorophenyl)-2H-1,2,3-triazole-4-carboxylic acid (CAS 72211-45-1)
- 1-(Thieno[3,2-c]pyridin-2-yl)ethan-1-amine (CAS 1313726-88-3)
- 4-Chloro-N-methylbenzenesulfonamide (CAS 6333-79-5)
- 1,7-Dihydroxy-3-methoxyacridin-9(10H)-one (CAS 612541-97-6)
- (R)-2-((tert-butoxycarbonyl)amino)-3-(3-chloro-4-hydroxyphenyl)propanoic acid (CAS 478183-57-2)
- Semaglutide impurity 194 (CAS CATO-C4X-2226194)
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