Apremilast Impurity 44 CAS 2096492-44-1
| CAS No. | 2096492-44-1 |
| Molecular Formula | C22H24N2O8S |
| Molecular Weight | 476.50 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 476.50 g/mol gives Apremilast Impurity 44 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Apremilast Impurity 44 (CAS 2096492-44-1, C22H24N2O8S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C22H24N2O8S, Apremilast Impurity 44 contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 476.50 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H24N2O8S |
| Molecular Weight | 476.50 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Apremilast Standards
- Apremilast Impurity 115 (CAS 1384814-94-1)
- Apremilast Impurity 32 (CAS CATO-C4X-100932)
- Apremilast Impurity 83 (CAS 2096492-43-0)
- Apremilast impurity 10 (CAS CATO-C4X-100910)
- Apremilast Impurity 69 (CAS CATO-C4X-100969)
- Apremilast Impurity 6 (CAS 1809170-71-5)
- Apremilast Impurity 7 (CAS 2096492-41-8)
- Apremilast-d8 (CAS 1258597-45-3)
Recommended Standards
- 4,4'-(((Phenylphosphinediyl)bis(4,1-phenylene))bis(oxy))dianiline (CAS 121566-10-7)
- 5-Benzyl-3-{4-[(4-fluorophenyl)methoxy]-3-methoxyphenyl}-2-methyl-hexahydro-2H-pyrrolo[3,4-d][1,2]oxazole-4,6-dione (CAS 317821-81-1)
- Canagliflozin Impurity 13 (CAS 2247196-28-5)
- 5,5'-Thiobis(2-phenylisoindoline-1,3-dione) (CAS 58974-89-3)
- Finerenone Impurity 183 (CAS CATO-C4X-2880183)
- CAS 1484216-96-7 (CAS 1484216-96-7)
- Valganciclovir EP Impurity Q Isomer (CAS CATO-C4X-177430)
- 2-Bromo-5-methoxybenzophenone (CAS 60080-98-0)
- n-Isobutyl-2-((tetrahydro-2h-pyran-4-yl)amino)acetamide (CAS 1153231-24-3)
- 1-(3-(2-Methoxyethoxy)phenyl)piperazine dihydrochloride (CAS 1187931-50-5)
- 6-(2-Methoxyethoxy)pyridine-3-carbonitrile (CAS 1016772-36-3)
- N-(3,5-Bis(trifluoromethyl)phenyl)-3-ethynylbenzamide (CAS 2499499-14-6)
- 6,7-Dimethyl-2,3-dihydrobenzofuran-2-carboxylic acid (CAS 26018-57-5)
- (10-31)Semaglutide (CAS CATO-C4X-2226283)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com