Tenofovir disoproxil Impurity 3 CAS 211364-69-1（free base）
| CAS No. | 211364-69-1（free base） |
| Molecular Formula | C14H22N5O7P |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Tenofovir disoproxil Impurity 3 (CAS 211364-69-1（free base）), a pharmacopoeial impurity reference standard (molecular formula C14H22N5O7PC4H4O4, MW 519.40 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, Tenofovir disoproxil Impurity 3 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 519.40 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Tenofovir disoproxil Impurity 3 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H22N5O7P C4H4O4 |
| Molecular Weight | 519.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Tenofovir Standards
- Tenofovir alafenamide Impurity 79 (CAS 102-10-3)
- rac Tenofovir-d6 (CAS 1020719-94-1)
- Tenofovir disoproxil Impurity 142 (CAS 102537-97-3)
- Tenofovir Disoproxil Dimer (CAS 1093279-76-5)
- Tenofovir disoproxil Impurity 6 (CAS 1093279-77-6)
- Tenofovir disoproxil Impurity 28 (CAS 1115-59-9)
- Tenofovir Impurity 59 (CAS 116384-56-6)
- Tenofovir alafenamide impurity 85 (CAS 121149-98-2)
Recommended Standards
- CAS 2204368-96-5 (CAS 2204368-96-5)
- Abemaciclib Impurity 187 (CAS CATO-C4X-2937187)
- Haloperidol Decanoate EP Impurity H (CAS 1134807-34-3)
- 2-[(3-Chlorophenyl)methyl]-4-{[(2,4-dichlorophenyl)methyl]sulfanyl}quinazoline (CAS 303149-49-7)
- 3-(4-methoxyphenylmethyl)-5-methyl-1,2,4-oxadiazole 82680-19-1 (CAS 82680-19-1)
- tert-Butyl (R)-2-(4-methylbenzyl)piperazine-1-carboxylate (CAS 1240589-58-5)
- 6-(Chloromethyl)thiazolo[3,2-b][1,2,4]triazole (CAS 170658-31-8)
- 2-Isopropyl-1H-imidazole-4-carboxamide (CAS 124709-76-8)
- 1-(5-Chloro-2-methylphenyl)-5-oxopyrrolidine-3-carboxylic acid (CAS 63675-00-3)
- Ginseng Tetrapeptide (CAS 178553-95-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com