Dasatinib Impurity 57 CAS 2135905-86-9
| CAS No. | 2135905-86-9 |
| Molecular Formula | C20H21ClN8O2S |
| Molecular Weight | 472.95 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Dasatinib Impurity 57 (C20H21ClN8O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Dasatinib Impurity 57 (CAS 2135905-86-9) is a certified pharmaceutical impurity reference standard with the molecular formula C20H21ClN8O2S and a molecular weight of 472.95 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Dasatinib Impurity 57 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H21ClN8O2S |
| Molecular Weight | 472.95 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 8 |
| Sulfur Atoms | 1 |
Related Dasatinib Standards
- Dasatinib Impurity 72 (CAS CATO-C4X-160772)
- Dasatinib Impurity 38 (CAS 1159977-25-9)
- Dasatinib Impurity 45 (CAS 1025814-13-4)
- Dasatinib (CAS 302962-49-8)
- Dasatinib Impurity 31 (CAS CATO-C4X-160731)
- Dasatinib Impurity 32 (CAS 2468737-83-7)
- Dasatinib Impurity 36 (CAS 2048106-50-7)
- Dasatinib Impurity 70 (CAS CATO-C4X-160770)
Recommended Standards
- Lapatinib Impurity 37 (CAS 1268997-70-1)
- 6,8-Dibromo-3-(4-bromobenzyl)quinazolin-4(3H)-one (CAS 302913-27-5)
- Methyl 5-((3-chloro-4-methylphenyl)carbamoyl)-2-(3-methoxybenzamido)-4-methylthiophene-3-carboxylate (CAS 332923-77-0)
- N-(3-chlorobenzyl)-6-(ethylsulfonyl)-4-(methylsulfonyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxamide (CAS 866134-37-4)
- Paliperidone Impurity 103 (CAS CATO-C4X-1724103)
- Avanafil Impurity 5 (CAS 372117-54-9)
- Lumateperone Impurity 48 (CAS 2702323-64-4)
- 1-(1-Benzyl-1H-indol-6-yl)-N-methylmethanamine (CAS 1485426-24-1)
- Methyl 2-bromo-3',5'-dichlorophenylacetate (CAS 929048-72-6)
- 4-(Difluoromethyl)pyrimidine-2-carbonitrile (CAS 1416821-61-8)
- N4-Benzoyl-5-O-tert-butyldimethylsilyl-2-deoxycytidine (CAS 51549-36-1)
- [2,2'-Binaphthalen]-6-yl trifluoromethanesulfonate (CAS 935472-81-4)
- 3-{[3-(Trifluoromethyl)benzyl]oxy}benzoic acid (CAS 1039850-23-1)
- Semaglutide impurity 69 (CAS CATO-C4X-222669)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com