Empagliflozin Impurity 77 CAS 2137418-13-2
| CAS No. | 2137418-13-2 |
| Molecular Formula | C23H27ClO8 |
| Molecular Weight | 466.91 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Empagliflozin Impurity 77 (CAS 2137418-13-2), a pharmacopoeial impurity reference standard (molecular formula C23H27ClO8, MW 466.91 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C23H27ClO8, Empagliflozin Impurity 77 contains a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 466.91 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H27ClO8 |
| Molecular Weight | 466.91 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Cl-containing |
Related Empagliflozin Standards
- Empagliflozin Impurity 170 (CAS 1620758-30-6)
- Empagliflozin impurity 181 (CAS 2452301-36-7)
- Empagliflozin impurity 188 (CAS CATO-C4X-1065188)
- Empagliflozin impurity 189 (CAS CATO-C4X-1065189)
- Empagliflozin impurity 206 (CAS CATO-C4X-1065206)
- Empagliflozin impurity 210 (CAS CATO-C4X-1065210)
- Empagliflozin Impurity 218 (CAS CATO-C4X-1065218)
- Empagliflozin impurity 224 (CAS CATO-C4X-1065224)
Recommended Standards
- Empagliflozin Impurity 49 (CAS 1279691-35-8)
- Empagliflozin Impurity 87 (CAS CATO-C4X-106587)
- Amlodipine Impurity 108 (CAS 88150-61-2)
- Ertugliflozin impurity 40 (CAS CATO-C4X-301140)
- Dobutamine Impurity 53 (CAS CATO-C4X-129853)
- Landiolol Impurity 97 (CAS CATO-C4X-262197)
- Brivaracetam Impurity 130 (CAS CATO-C4X-2007130)
- Methyl 3-(1H-pyrrol-3-yl)propanoate (CAS 150985-69-6)
- 4-(Difluoromethyl)-5,6-diiodopicolinoyl chloride (CAS 1806823-36-8)
- 2-Ethyl-N-(thiazol-5-ylmethyl)aniline (CAS 1340292-46-7)
- Methyl (R)-3-amino-3-(4-(trifluoromethyl)phenyl)propanoate (CAS 1228543-08-5)
- ((5-Acetylfuran-2-yl)methyl)triphenylphosphonium bromide (CAS 114430-55-6)
- 4-Fluoro-3,5-bis(tributylstannyl)pyridine (CAS 1204580-75-5)
- [14-31]-Semaglutide (CAS CATO-C4X-2226262)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com