Empagliflozin Impurity 49 CAS 1279691-35-8
| CAS No. | 1279691-35-8 |
| Molecular Formula | C23H27ClO8 |
| Molecular Weight | 466.91 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Empagliflozin Impurity 49.
As a process- or degradation-related impurity, Empagliflozin Impurity 49 (CAS 1279691-35-8, C23H27ClO8) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Empagliflozin Impurity 49 (C23H27ClO8) contains a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 466.91 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Empagliflozin Impurity 49 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H27ClO8 |
| Molecular Weight | 466.91 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
Related Empagliflozin Standards
- Empagliflozin Impurity 170 (CAS 1620758-30-6)
- Empagliflozin impurity 181 (CAS 2452301-36-7)
- Empagliflozin impurity 188 (CAS CATO-C4X-1065188)
- Empagliflozin impurity 189 (CAS CATO-C4X-1065189)
- Empagliflozin impurity 206 (CAS CATO-C4X-1065206)
- Empagliflozin impurity 210 (CAS CATO-C4X-1065210)
- Empagliflozin Impurity 218 (CAS CATO-C4X-1065218)
- Empagliflozin impurity 224 (CAS CATO-C4X-1065224)
Recommended Standards
- Empagliflozin Impurity 77 (CAS 2137418-13-2)
- Empagliflozin Impurity 87 (CAS CATO-C4X-106587)
- Amlodipine Impurity 108 (CAS 88150-61-2)
- Ertugliflozin impurity 40 (CAS CATO-C4X-301140)
- Oxazepam EP Impurity B (CAS 1824-74-4)
- Cefadroxil Impurity 3 (CAS 2378158-44-0)
- Pentoxifylline Impurity 17 (CAS 1185995-26-9)
- 4-Amino-3-isobutoxy-N,N-dimethylbenzamide (CAS 1406158-74-4)
- 7443-52-9 Cyclohexanol, trans- NSC-244887 NSC244887 trans-2-Methylcyclohexanol (CAS 7443-52-9)
- Carboplatin Impurity 12 (CAS 113287-15-3)
- (R)-1-methoxybutan-2-amine (CAS 57883-06-4)
- 7-(Difluoromethoxy)quinoxalin-2(1H)-one (CAS 1558746-87-4)
- Decyl 2-(3-oxopiperazin-2-yl)acetate (CAS 1025736-41-7)
- Semaglutide impurity 29 (CAS 110990-08-4)
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