Cefpodoxime Proxetil EP Impurity E CAS 217803-89-9
| CAS No. | 217803-89-9 |
| Molecular Formula | C22H27N5O10S2 |
| Molecular Weight | 585.61 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Cefpodoxime Proxetil EP Impurity E.
Cefpodoxime Proxetil EP Impurity E (CAS 217803-89-9) is a certified pharmaceutical impurity reference standard with the molecular formula C22H27N5O10S2 and a molecular weight of 585.61 g/mol.
Cefpodoxime Proxetil EP Impurity E (C22H27N5O10S2) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Cefpodoxime Proxetil EP Impurity E meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H27N5O10S2 |
| Molecular Weight | 585.61 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2019 |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 2 |
Related Cefpodoxime Standards
- Cefpodoxime Proxetil EP Impurity E (CAS CATO-C4X-157951)
- Cefpodoxime Proxetil EP Impurity F (CAS CATO-C4X-157953)
- Cefpodoxime Proxetil EP Impurity F (CAS 96680-30-7)
- Cefpodoxime Impurity 60 (CAS CATO-C4X-157960)
- Cefpodoxime Impurity 62 (CAS CATO-C4X-157962)
- Cefpodoxime Proxetil Impurity 10 (CAS CATO-C4X-157910)
- Cefpodoxime Impurity 48 (CAS CATO-C4X-157948)
- Cefpodoxime Impurity 50 (CAS CATO-C4X-157950)
Recommended Standards
- Nafamostat impurity 87 (CAS CATO-C4X-133287)
- Nafamostat Impurity 27 (CAS CATO-C4X-133227)
- Methotrexate Impurity 82 (CAS CATO-C4X-115482)
- Fosamprenavir (CAS 226700-79-4)
- Formoterol Impurity 29 HCl (CAS 43229-67-0(free base))
- Ifosfamide Impurity 4 (CAS CATO-C4X-20014)
- Fexofenadine Impurity 19 (CAS CATO-C4X-179419)
- 7-amino-1-oxo-1,2-dihydroisoquinoline-4-carboxylic acid (CAS 1545047-94-6)
- 3-Fluoro-1-phenylcyclobutane-1-carboxylic acid (CAS 1552638-76-2)
- 4-[(3-Iodophenoxy)methyl]piperidine (CAS 1347292-97-0)
- 1-(Difluoromethyl)-4-methylnaphthalene (CAS 1221272-85-0)
- 5,6,7,8-Tetrahydroisoquinolin-4-amine dihydrochloride (CAS 1159822-63-5)
- Tridecylbenzene (CAS 123-02-4)
- Hexapeptide-9 (CAS 1228371-11-6)
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